5673-07-4 Usage
Description
2,6-Dimethoxytoluene, also known as methylanisole, is an organic compound belonging to the aromatic family. It is a light yellow to brownish crystalline solid with a distinct aromatic odor. 2,6-DIMETHOXYTOLUENE is characterized by its two methoxy groups (-OCH3) attached to the benzene ring at the 2nd and 6th positions, which contribute to its unique chemical properties and reactivity.
Uses
Used in Chemical Synthesis:
2,6-Dimethoxytoluene is used as an organic chemical synthesis intermediate for various applications in the chemical industry. Its unique structure allows it to be a versatile building block for the synthesis of a wide range of compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Fragrance Industry:
Due to its pleasant aromatic odor, 2,6-dimethoxytoluene is also utilized in the fragrance industry as a component in the formulation of perfumes, colognes, and other scented products. Its ability to blend well with other fragrance ingredients makes it a valuable addition to the perfumer's palette.
Used in Dyes and Pigments:
2,6-DIMETHOXYTOLUENE's aromatic nature and chemical structure make it suitable for use in the production of dyes and pigments. It can be employed as a starting material or intermediate in the synthesis of various colorants used in the textile, plastics, and printing industries.
Used in Laboratory Research:
2,6-Dimethoxytoluene is also used in laboratory research as a reagent or starting material for the synthesis of various organic compounds. Its availability and relatively simple structure make it a popular choice for researchers working on the development of new chemical entities and materials.
Synthesis Reference(s)
Journal of the American Chemical Society, 78, p. 771, 1956 DOI: 10.1021/ja01585a020
Purification Methods
Sublime 2,6-dimethoxytoluene in vacuo. Distil it (preferably under reduced pressure) and/or recrystallise it from pentane, EtOH or aqueous MeOH. [Sankaraman et al. J Am Chem Soc 109 5235 1987]. [Beilstein 6 H 872, 6 III 4513, 6 IV 5877.]
Check Digit Verification of cas no
The CAS Registry Mumber 5673-07-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,7 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5673-07:
(6*5)+(5*6)+(4*7)+(3*3)+(2*0)+(1*7)=104
104 % 10 = 4
So 5673-07-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H12O2/c1-7-8(10-2)5-4-6-9(7)11-3/h4-6H,1-3H3
5673-07-4Relevant articles and documents
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Kessler,H. et al.
, p. 287 - 293 (1969)
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Mild partial deoxygenation of esters catalyzed by an oxazolinylborate-coordinated rhodium silylene
Xu, Songchen,Boschen, Jeffery S.,Biswas, Abhranil,Kobayashi, Takeshi,Pruski, Marek,Windus, Theresa L.,Sadow, Aaron D.
supporting information, p. 15897 - 15904 (2015/09/15)
An electrophilic, coordinatively unsaturated rhodium complex supported by borate-linked oxazoline, oxazoline-coordinated silylene, and N-heterocyclic carbene donors [{κ3-N,Si,C-PhB(OxMe2)(OxMe2SiHPh)ImMes}Rh(H)CO][HB(C6F5)3] (2, OxMe2 = 4,4-dimethyl-2-oxazoline; ImMes = 1-mesitylimidazole) is synthesized from the neutral rhodium silyl {PhB(OxMe2)2ImMes}RhH(SiH2Ph)CO (1) and B(C6F5)3. The unusual oxazoline-coordinated silylene structure in 2 is proposed to form by rearrangement of an unobserved isomeric cationic rhodium silylene species [{PhB(OxMe2)2ImMes}RhH(SiHPh)CO][HB(C6F5)3] generated by H abstraction. Complex 2 catalyzes reductions of organic carbonyl compounds with silanes to give hydrosilylation products or deoxygenation products. The pathway to these reactions is primarily influenced by the degree of substitution of the organosilane. Reactions with primary silanes give deoxygenation of esters to ethers, amides to amines, and ketones and aldehydes to hydrocarbons, whereas tertiary silanes react to give 1,2-hydrosilylation of the carbonyl functionality. In contrast, the strong Lewis acid B(C6F5)3 catalyzes the complete deoxygenation of carbonyl compounds to hydrocarbons with PhSiH3 as the reducing agent.
Phenyl benzisoxazoles as estrogenic agents
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Page/Page column 19, (2010/11/30)
This invention provides estrogen receptor modulators of formula I, having the structure wherein, R1, R2, and R3 are as defined in the specification, or a pharmaceutically acceptable salt thereof.
