57076-48-9

Basic information

• Product Name: 3-chlorophenyl trifluoroacetates
• Synonyms: 3-chlorophenyl trifluoroacetates
• CAS NO: 57076-48-9
• Molecular Weight: 224.567
• Mol File: 57076-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chlorophenyl trifluoroacetates(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chlorophenyl trifluoroacetates(57076-48-9)
• EPA Substance Registry System: 3-chlorophenyl trifluoroacetates(57076-48-9)

Safety Data

• Hazardous Substances Data: 57076-48-9(Hazardous Substances Data)

Upstream product

• 108-43-0 3-monochlorophenol 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 108-43-0 3-monochlorophenol 
• 76-05-1 trifluoroacetic acid 

Relevant articles and documents

Neutral Hydrolysis of Substituted Phenyl Trifluoroacetates in Water-Acetonitrile Mixtures with Low Content of Water

The neutral hydrolysis of substituted phenyl trifluoroacetates has been studied in water-acetonitrile mixtures in the region 0.56-3.89M water.The large solvent deuterium isotope effect (kH2O/kD2O) of 2.3 and the thermodynamic activation parameters for the hydrolysis of 4-nitrophenyl and 2,4-dinitrophenyl trifluoroacetates are consistent with a reaction mechanism in which one water molecule acts as a nucleophile and one as a general base.A linear correlation with a slope of 3.4 is found between log kobs and log for the hydrolysis of 4-nitrophenyl trifluoroacetate.This indicates the incorporation of several water molecules in the transition state.The effect of the structure of the leaving group on the rate of the reaction is best explained by a rate-limiting attack on the carbonyl group.