59860-91-2

Basic information

• Product Name: 9α-fluoro-3,11β,17α,21-tetrahydroxy-16β-methyl-1,3,5-pregnatriene-20-one 21-acetate 3-benzoate
• CAS NO: 59860-91-2
• Molecular Weight: 538.613
• Mol File: 59860-91-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 9α-fluoro-3,11β,17α,21-tetrahydroxy-16β-methyl-1,3,5-pregnatriene-20-one 21-acetate 3-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 9α-fluoro-3,11β,17α,21-tetrahydroxy-16β-methyl-1,3,5-pregnatriene-20-one 21-acetate 3-benzoate(59860-91-2)
• EPA Substance Registry System: 9α-fluoro-3,11β,17α,21-tetrahydroxy-16β-methyl-1,3,5-pregnatriene-20-one 21-acetate 3-benzoate(59860-91-2)

Safety Data

• Hazardous Substances Data: 59860-91-2(Hazardous Substances Data)

Upstream product

• 987-24-6 betamethasone 21-acetate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 72560-07-7 9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-benzoate 
• 82926-63-4 9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-butyrate 
• 72559-76-3 9α-fluoro-6β,11β,17α,21-tetrahydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 21-acetate 

Relevant articles and documents

Synthesis and topical antiinflammatory potencies of a series of 6-keto- and Δ6-6-acyloxybetamethasone derivatives

6-Keto and Δ6-6-acyloxybetamethasone esters were synthesized, and tested for topical antiinflammatory potency using a modification of the Tonelli croton ear assay. The introduction of a 6-keto group generally led to retention of topical antiinflammatory potencies when compared to the corresponding 6-desoxycorticoids. In contrast, introduction of the Δ6-6-acyloxy moiety into betamethasone 17,21-dipropionate reduced antiinflammatory potency.