6028-61-1

Basic information

• Product Name: Dipropyl trisulfide
• Synonyms: FEMA 3276;DIPROPYL TRISULFIDE;DIPROPYL TRISULPHIDE;1,3-Dipropyltrisulfane;Di-n-propyl trisulfide;Trisulfide, dipropyl;PROPYL TRISULFIDE;PROPYL TRITHIO PROPANE
• CAS NO: 6028-61-1
• Molecular Formula: C₆H₁₄S₃
• Molecular Weight: 182.37
• EINECS: 227-903-4
• Product Categories: sulfide Flavor
• Mol File: 6028-61-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 256.8 °C at 760 mmHg
• Flash Point: 106.1 °C
• Appearance: COA
• Density: 1.076 g/cm³
• Vapor Pressure: 0.0243mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: 2-8°C
• BRN: 1736293
• CAS DataBase Reference: Dipropyl trisulfide(CAS DataBase Reference)
• NIST Chemistry Reference: Dipropyl trisulfide(6028-61-1)
• EPA Substance Registry System: Dipropyl trisulfide(6028-61-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• RTECS: UK3870000
• Hazardous Substances Data: 6028-61-1(Hazardous Substances Data)

Usage

Description

Dipropyl trisulfide is a chemical compound with a very powerful, diffusive, garlic-like odor. It is a volatile constituent found in various Allium species, such as onion, shallot, leek, and chive, as well as in roasted peanut and durian. Dipropyl trisulfide has taste characteristics at 2.0 ppm, which are alliaceous, sulfurous, green, and garlic-like, with a tin-like metallic undertone and minty and tropical nuances.

Uses

1. Used in the Food Industry:
Dipropyl trisulfide is used as a flavoring agent for its strong garlic-like odor and taste, enhancing the flavor of various dishes and food products.
2. Used in the Agricultural Industry:
Dipropyl trisulfide is used as a preservative for cut potatoes, providing antibrowning and antimicrobial effects to maintain the quality and freshness of the produce.
3. Used in the Chemical Industry:
Dipropyl trisulfide can be utilized as a chemical intermediate for the synthesis of other organic compounds, taking advantage of its unique sulfur-containing structure.
4. Used in the Aromatherapy Industry:
Due to its strong and distinctive odor, Dipropyl trisulfide may be used in the formulation of aromatherapy products, potentially offering therapeutic benefits related to its scent.
5. Used in the Research and Development Industry:
Dipropyl trisulfide can be employed in research studies focusing on the properties and applications of sulfur-containing compounds, as well as their potential effects on various biological systems.

Preparation

By adaptation of Westlake’s procedure.

Synthesis Reference(s)

The Journal of Organic Chemistry, 22, p. 145, 1957 DOI: 10.1021/jo01353a011

InChI:InChI=1/C6H14S3/c1-3-5-7-9-8-6-4-2/h3-6H2,1-2H3

Upstream product

• 107-03-9 1-thiopropane 
• 624-92-0 Dimethyldisulphide 
• 629-19-6 Dipropyl disulfide 
• 37981-36-5 (Z,Z)-bis-(1-propenyl) sulfide 
• 106-94-5 propyl bromide 
• 66304-00-5 1-oxo-1H-1λ⁴-benzo[1,2]dithiol-3-one 
• 7783-06-4 hydrogen sulfide 
• 123-38-6 propionaldehyde 
• 205105-91-5 5-methyl-1-oxo-1H-1λ⁴-benzo[1,2]dithiol-3-one 
• 863478-23-3 7-methyl-1-oxo-1H-1λ⁴-benzo[1,2]dithiol-3-one 
• 863478-26-6 5-methoxy-1-oxo-1H-1λ⁴-benzo[1,2]dithiol-3-one 
• 863478-25-5 5-chloro-1-oxo-1H-1λ⁴-benzo[1,2]dithiol-3-one 
• 863478-24-4 7-methoxy-1-oxo-1H-1λ⁴-benzo[1,2]dithiol-3-one 
• 863478-22-2 7-chloro-1-oxo-1H-1λ⁴-benzo[1,2]dithiol-3-one 

Downstream Products

• 4154-77-2 hexaethyl-thiophosphamide 
• 629-19-6 Dipropyl disulfide 
• 534-25-8 1,2-dithiole-3-thione 
• 107-03-9 1-thiopropane 
• 111-47-7 propyl sulfide 
• 75030-40-9 benzyl n-propyl trisulfide 
• 27657-11-0 1-benzyl-2-propyldisulfane 
• 30453-31-7 ethyl propyl disulfide 
• 20195-06-6 O,O-diethyl-S-n-propyl phosporothiolate 

Relevant articles and documents

Key Odor-Active Compounds in Raw Green and Red Toona sinensis (A. Juss.) Roem. And Their Changes during Blanching

Application of aroma extract dilution analysis and headspace aroma dilution analysis revealed 51 odorants in raw green Toona sinensis and 54 odorants in raw red T. sinensis in the flavor dilution factor range of 8-4096. (E,E)-2,4-Decadienal, nonanal, 2,3,5-trimethylpyrazine, (E,Z)- and (Z,Z)-di-1-propenyl trisulfide, 2-methoxyphenol, and 4-ethylphenol were first identified as key odorants of T. sinensis. Clear differences between green and red T. sinensis in aroma profiles, flavor dilution factors, quantitative data, and odor activity values verified that (E,E)-, (E,Z)-, and (Z,Z)-di-1-propenyl disulfide, (E,E)-, (E,Z)- and (Z,Z)-di-1-propenyl trisulfide, cis- and trans-2-mercapto-3,4-dimethyl-2,3-dihydrothiophene, and dimethyl sulfide caused the distinct sulfury odor note of each variety. Further, hexanal, (E)-2-hexenal, (E)-2-hexen-1-ol, and (E,Z)-2,6-nonadienal led to the green odor note in green T. sinensis, while 2-methoxyphenol and 4-ethylphenol contributed to the intense phenolic aroma note in red T. sinensis. Quantitation experiments and triangle tests in blanched T. sinensis verified that the quick loss of the abovementioned sulfur-containing compounds, aldehydes, the alcohol (E)-2-hexen-1-ol, and phenols was responsible for the changes in the overall aroma profile during blanching.

Trisulfides over disulfides: Highly selective synthetic strategies, anti-proliferative activities and sustained H2S release profiles

Temperature-and solvent-induced selective synthesis of trisulfides and disulfides is demonstrated. A remarkable selectivity was achieved using Na2S as a sulfur-Transfer agent under mild, greener, catalyst-free and additive-free conditions. This study reveals trisulfides as a better model than disulfides in general for a sustained release of H2S and potent anti-cancer activities.

Unusual Reaction Route of Unsaturated Amines with Hydrogen Sulfide

-