60307-59-7Relevant articles and documents
Manganese-Catalyzed α-Olefination of Nitriles with Secondary Alcohols
Balaraman, Ekambaram,Landge, Vinod G.,Subaramanian, Murugan,Yadav, Vinita
, p. 947 - 954 (2020/01/13)
An expedient catalytic approach for α-olefination of nitriles using secondary alcohols with the liberation of molecular hydrogen and water as the only byproducts is reported. This reaction is catalyzed by a molecularly defined manganese(I) pincer complex and operates in the absence of any hydrogen acceptors. A broad range of substrates including cyclic, acyclic, and benzylic alcohols, as well as various nitrile derivatives, such as arylmethyl and heteroarylmethyl nitriles, are employed in the reaction to provide a diverse range of α-vinyl nitriles in good to excellent yields. Mechanistic studies showed that the reaction proceeds via dehydrogenative pathway and the activation of α(C-H) bond of the alcohol is the rate-determining step.
A New Olefin Synthesis. Synchronous Elimination of Nitro and Ester Groups or Nitro and Keto Groups from β-Nitro Esters or β-Nitro Ketones
Ono, Noboru,Tamura, Rui,Eto, Hiromichi,Hamamoto, Isami,Nakatsuka, Tamon,et al.
, p. 3678 - 3684 (2007/10/02)
A new synthesis of α,β-unsaturated nitriles (13), esters (14), ketones (15), or sulfones (16) 1R2C=CR3Y, Y = CN (13), Y = COOEt (14), Y = C(=O)R (15), Y = SO2R (16)> starting from α-bromonitroalkanes (1) or α-chloronitro
