606124-81-6Relevant articles and documents
DIPEPTIDYL PEPTIDASE INHIBITORS
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Page 81, (2010/02/08)
The present invention relates to novel inhibitors of serine type peptidases in general and of serine type dipeptidyl peptidases in particular. The present invention further relates to the use of the dipeptidyl peptidase inhibitors for selective inhibition
Modular ligands derived from amino acids for the enantio selective addition of organozinc reagents to aldehydes
Richmond, Meaghan L.,Seto, Christopher T.
, p. 7505 - 7508 (2007/10/03)
A new series of modular chiral ligands that are derived from amino acids were prepared and tested for their ability to catalyze the asymmetric addition of alkylzinc reagents to aromatic and aliphatic aldehydes. The ligands contain a tertiary amine, an amino acid side chain, and a carbamate or amide functional group. One ligand, which was synthesized from Ile, catalyzes the addition of diethylzinc to cyclohexanecarboxaldehyde in 99% ee.