61315-61-5 Usage
Description
BOC-D-Arg(Tos)-OH, also known as Nα-(tert-Butoxycarbonyl)-D-arginine p-toluenesulfonate, is a synthetic derivative of the naturally occurring amino acid L-arginine. It features a tert-butoxycarbonyl (BOC) protecting group and a p-toluenesulfonate (Tos) group attached to the D-arginine molecule. BOC-D-Arg(Tos)-OH is characterized by its chiral structure and unique functional groups, which make it a versatile building block in various chemical and pharmaceutical applications.
Uses
Used in Chemical Synthesis:
BOC-D-Arg(Tos)-OH is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows for selective reactions and modifications, facilitating the development of novel molecules with desired properties.
Used in Peptide Chemistry:
In the field of peptide chemistry, BOC-D-Arg(Tos)-OH serves as a crucial building block for the synthesis of peptide-based drugs, therapeutic agents, and diagnostic tools. The BOC protecting group can be selectively removed under mild conditions, enabling the stepwise assembly of complex peptide sequences. The D-arginine residue, with its positively charged guanidinium group, can also impart specific biological activities and interactions with target molecules.
Used in Pharmaceutical Industry:
BOC-D-Arg(Tos)-OH is used as a precursor in the development of new drugs targeting various diseases and conditions. Its unique structure and functional groups can be exploited to design molecules with improved pharmacokinetics, selectivity, and potency. BOC-D-Arg(Tos)-OH can also be used to study the structure-activity relationships of arginine-containing bioactive molecules, aiding in the optimization of drug candidates.
Used in Research and Development:
BOC-D-Arg(Tos)-OH is employed as a valuable research tool in academic and industrial laboratories. It can be used to investigate the role of arginine in biological processes, such as enzyme catalysis, protein-protein interactions, and signal transduction pathways. BOC-D-Arg(Tos)-OH can also be utilized to develop new synthetic methodologies and strategies for the preparation of complex organic molecules and bioactive peptides.
Check Digit Verification of cas no
The CAS Registry Mumber 61315-61-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,1 and 5 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 61315-61:
(7*6)+(6*1)+(5*3)+(4*1)+(3*5)+(2*6)+(1*1)=95
95 % 10 = 5
So 61315-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H28N4O6S/c1-12-7-9-13(10-8-12)29(26,27)22-16(19)20-11-5-6-14(15(23)24)21-17(25)28-18(2,3)4/h7-10,14H,5-6,11H2,1-4H3,(H,21,25)(H,23,24)(H3,19,20,22)/t14-/m1/s1
61315-61-5Relevant articles and documents
LHRH analogs
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, (2008/06/13)
The present invention relates to novel ""pseudo"" nonapeptide and decapeptide derivatives of LHRH. More particularly the present invention relates to derivatives of LHRH wherein the nitrogen atom of at least one of the amide bonds has been alkylated.
