627-19-0 Usage
Description
1-Pentyne, also known as pent-1-yne, is an organic compound belonging to the alkyne family. It is a clear colorless to pale yellow liquid with the molecular formula C5H8. 1-Pentyne is characterized by the presence of a carbon-carbon triple bond, which makes it a versatile building block in organic synthesis.
Uses
1-Pentyne is used as a synthetic building block for the preparation of various organic compounds, including:
Lithium acetylides, which are essential for the asymmetric synthesis of α,α-dibranched propargyl sulfinamides. These compounds have potential applications in the pharmaceutical industry for the development of new drugs.
7-hydroxy-10-methoxy-3H-naphtho[2.1-b]pyrans, which are organic compounds with potential applications in the chemical and pharmaceutical industries.
In the Chemical Industry:
1-Pentyne is used as a starting material for the synthesis of various organic compounds, taking advantage of its triple bond reactivity. The selective and non-selective hydrogenation of 1-pentyne, catalyzed by silica-supported palladium, has been studied using in situ X-ray absorption spectroscopy, demonstrating its importance in the development of new synthetic methods and catalysts.
In the Pharmaceutical Industry:
1-Pentyne plays a crucial role in the synthesis of complex organic molecules, which can be further utilized in the development of new drugs. Its ability to form lithium acetylides for the asymmetric synthesis of α,α-dibranched propargyl sulfinamides highlights its potential in creating novel pharmaceutical compounds with specific biological activities.
In the Research and Development Sector:
1-Pentyne serves as a valuable compound for researchers in the field of organic chemistry, allowing them to explore new synthetic pathways and develop innovative methods for the preparation of complex molecules. Its unique chemical properties make it an essential tool in the advancement of scientific knowledge and the discovery of new applications in various industries.
Safety Profile
Dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes. See also ACETYLENE COMPOUNDS
Check Digit Verification of cas no
The CAS Registry Mumber 627-19-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 627-19:
(5*6)+(4*2)+(3*7)+(2*1)+(1*9)=70
70 % 10 = 0
So 627-19-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H8/c1-3-5-4-2/h1H,4-5H2,2H3
627-19-0Relevant articles and documents
Unexpected conformational behavior of gaseous 1-pentyne
Traetteberg,Bakken,Hopf
, p. 213 - 220 (1999)
The molecular structure and conformations of 1-pentyne have been studied experimentally by the gas electron diffraction method. A conformational mixture of 68.6% gauche and 31.4% anti, with standard deviation equal to 4.5%, was observed. Results from ab initio MP2/6-31G* optimization calculations are in excellent agreement with those observed.
TiO2 Assisted Photocatalytic Decomposition of 2-Chloronaphthalene on Iron Nanoparticles in Aqueous Systems: Synergistic Effect and Intermediate Products
Jipeng Qi,Wang, Chen,Sun, Jing,Li, Shuping
, p. 1620 - 1626 (2019/08/15)
Abstract: 2-Chloronaphthalene (2-CN), used as an intermediate for organic synthesis, is a new type of persistent organic pollutant. In this work, the decomposition efficiency and decomposition mechanism of 2-CN by zero-valent iron (ZVI) assisted TiO2
Controlled photorelease of alkynoic acids and their decarboxylative deprotection for copper-catalyzed azide/alkyne cycloaddition
Vohradská, Nikoleta,Sánchez-Carnerero, Esther M.,Pastierik, Tomá?,Mazal, Ctibor,Klán, Petr
supporting information, p. 5558 - 5561 (2018/06/04)
A controlled photorelease of alkynoic acids from the meso-methyl BODIPY photoremovable protecting group facilitates their subsequent efficient decarboxylation to give terminal alkynes for a CuI-catalyzed azide/alkyne cycloaddition. The quantum efficiencies of the photochemical step and the kinetics of the click reaction step are reported.