6275-82-7

Basic information

• Product Name: 4-[(cyanomethyl)amino]benzoic acid
• CAS NO: 6275-82-7
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.172
• Mol File: 6275-82-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 440.5°C at 760 mmHg
• Flash Point: 220.2°C
• Density: 1.341g/cm³
• Vapor Pressure: 1.55E-08mmHg at 25°C
• Refractive Index: 1.64
• CAS DataBase Reference: 4-[(cyanomethyl)amino]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(cyanomethyl)amino]benzoic acid(6275-82-7)
• EPA Substance Registry System: 4-[(cyanomethyl)amino]benzoic acid(6275-82-7)

Safety Data

• Hazardous Substances Data: 6275-82-7(Hazardous Substances Data)

Upstream product

• 110-88-3 1,3,5-Trioxan 
• 151-50-8 potassium cyanide 
• 150-13-0 4-amino-benzoic acid 
• 50-00-0 formaldehyd 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 23284-85-7 4-((2-ethoxy-2-oxoethyl)amino)benzoic acid 
• 5698-54-4 N-(p-carboxyphenyl)glycine 
• 26815-64-5 ethyl 4-benzoate 

Relevant articles and documents

Design and Synthesis of Iminosydnones for Fast Click and Release Reactions with Cycloalkynes

Emerging applications in the field of chemical biology are currently limited by the lack of bioorthogonal reactions allowing both removal and linkage of chemical entities on complex biomolecules. We recently discovered a novel reaction between iminosydnones and strained alkynes leading to two products resulting from ligation and fragmentation of iminosydnones under physiological conditions. We now report the synthesis of a panel of substituted iminosydnones and the structure reactivity relationship between these compounds and strained alkyne partners. This study identified the most relevant substituents, which allow to increase the rate of the transformation and to develop a bifunctional cleavable linker with improved kinetics.