63218-14-4

Basic information

• Product Name: 2-(4-NITROPHENOXY)ACETAMIDE
• Synonyms: TIMTEC-BB SBB000350;2-(4-NITROPHENOXY)ACETAMIDE;(4-Nitrophenoxy)acetamide
• CAS NO: 63218-14-4
• Molecular Formula: C₈H₈N₂O₄
• Molecular Weight: 196.16
• Mol File: 63218-14-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 157 °C
• Boiling Point: 463.6±25.0 °C(Predicted)
• Appearance: /
• Density: 1.375±0.06 g/cm3(Predicted)
• PKA: 14.71±0.40(Predicted)
• CAS DataBase Reference: 2-(4-NITROPHENOXY)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-NITROPHENOXY)ACETAMIDE(63218-14-4)
• EPA Substance Registry System: 2-(4-NITROPHENOXY)ACETAMIDE(63218-14-4)

Safety Data

• Hazardous Substances Data: 63218-14-4(Hazardous Substances Data)

Usage

General Description

2-(4-NITROPHENOXY)ACETAMIDE is a chemical compound with the molecular formula C8H8N2O4. It is a white to light yellow crystalline powder that is soluble in organic solvents. 2-(4-NITROPHENOXY)ACETAMIDE is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential use as an anti-inflammatory agent and for its ability to inhibit the growth of cancer cells. Additionally, 2-(4-NITROPHENOXY)ACETAMIDE has been used in the production of dyes and pigments due to its ability to react with other chemicals to produce vibrant colors. Overall, this compound has a range of potential applications in various industries.

Upstream product

• 20142-88-5 2-(4-nitrophenoxy)acetyl chloride 
• 100-02-7 4-nitro-phenol 
• 144-48-9 iodacetamide 
• 683-57-8 bromo-acetic acid amide 
• 33901-46-1 2-(4-nitrophenoxy)acetonitrile 
• 824-78-2 4-nitrophenol sodium salt 
• 79-07-2 Chloroacetamide 
• 1124-31-8 potassium 4-nitrophenolate 
• 1798-11-4 4-nitrophenoxyacetic acid 

Downstream Products

• 58232-55-6 4-(carbamoylmethoxy)aniline 
• 575473-01-7 N₄-(4-aminocarbonylmethyloxyphenyl)-2-chloro-5-fluoro-4-pyrimidineamine 
• 575473-00-6 2-chloro-N₄-(4-(cyanomethyloxy)phenyl)-5-fluoro-4-pyrimidineamine 
• 62100-58-7 Gca-pNA 
• 6033-85-8 (4-acetylamino-phenoxy)-acetic acid amide 

Relevant articles and documents

2,4-Pyrimidinediamine Compounds and Their Uses

The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.

COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY

The invention encompasses compounds having formula (I-V) and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.

Phosphorylamides, their preparation and use

A phosphorylamide derivative represented by the general formula (I): STR1 wherein R represents an amino group that may be substituted, or a salt thereof, possesses potent antibacterial activity against Helicobacter bacterium, especially Helicobacter pylori, and is useful for prevention or treatment of digestive diseases caused by Helicobacter bacterium, solely or in combination with an antacid or an acid secretion inhibitor.