639519-02-1

Basic information

• Product Name: (3S,4R)-3-benzyloxy-2,2,4-trimethylhex-5-en-1-ol
• CAS NO: 639519-02-1
• Molecular Weight: 248.365
• Mol File: 639519-02-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,4R)-3-benzyloxy-2,2,4-trimethylhex-5-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-3-benzyloxy-2,2,4-trimethylhex-5-en-1-ol(639519-02-1)
• EPA Substance Registry System: (3S,4R)-3-benzyloxy-2,2,4-trimethylhex-5-en-1-ol(639519-02-1)

Safety Data

• Hazardous Substances Data: 639519-02-1(Hazardous Substances Data)

Upstream product

• 639519-01-0 (3S,4R)-3-benzyloxy-2,2,4-trimethylhex-5-enoic acid methyl ester 
• 14002-80-3 Methyl 2,2-dimethyl-3-hydroxypropionate 
• 13865-20-8 methyl 2,2-dimethyl-3-oxopropanoate 
• 639518-93-7 (3S,4R)-3-hydroxy-2,2,4-trimethylhex-5-enoic acid methyl ester 
• 639518-90-4 (3S,4R)-3-acetoxy-2,2,4-trimethylhex-5-enoic acid methyl ester 

Relevant articles and documents

Asymmetric synthesis of (3S,4R,7S)-(-)-3-hydroxy-7-methoxy-2,2,4-trimethyl- decanoic acid, a plausible polyketide fragment of halipeptin A

The first enantioselective synthesis of (3S,4R,7S)-(-)-3-hydroxy-7-methoxy- 2,2,4-trimethyl-decanoic acid 4 in 11 steps and 6% overall yield, starting from commercially available methyl 2,2-dimethyl-3-hydroxy propionate 5 is described. The stereochemical flexible synthetic pathway involves a Brown's crotylboration reaction and a Corey-Bakshi-Shibata (CBS) oxazaborolidine-mediated reduction.