648428-53-9

Basic information

• Product Name: Silane, (1,1-dimethylethyl)dimethyl[phenyl[(trimethylsilyl)oxy]methyl]-
• CAS NO: 648428-53-9
• Molecular Formula: C16H30OSi2
• Molecular Weight: 294.585
• Mol File: 648428-53-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)dimethyl[phenyl[(trimethylsilyl)oxy]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)dimethyl[phenyl[(trimethylsilyl)oxy]methyl]-(648428-53-9)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)dimethyl[phenyl[(trimethylsilyl)oxy]methyl]-(648428-53-9)

Safety Data

• Hazardous Substances Data: 648428-53-9(Hazardous Substances Data)

Upstream product

• 53172-99-9 (+/-)-1-phenyl-1-(tert-butyldimethylsilyl)methanol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 75-77-4 chloro-trimethyl-silane 
• 53172-91-1 (benzyloxy)(tert-butyl)dimethylsilane 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 100-51-6 benzyl alcohol 
• 648428-84-6 (α,α-bromobenzyl)(tert-butyl)dimethylsilane 
• 435344-57-3 benzyl(tert-butyl)dimethylsilane 
• 100-44-7 benzyl chloride 
• 132868-67-8 (tert-butyldimethylsilyl)(phenyl)methanone 

Downstream Products

• 4358-87-6 (RS)-methyl mandelate 

Relevant articles and documents

Carboxylation with CO2 via brook rearrangement: Preparation of α-hydroxy acid derivatives

In the presence of CsF, a wide range of α-substituted α-siloxy silanes were carboxylated under a CO2 atmosphere (1 atm) via Brook rearrangement. A variety of α-substituents including aryl, alkenyl, and alkyl groups were tolerated to afford α-hydroxy acids in moderate-to-high yields. One-pot synthesis from aldehydes using PhMe2SiLi and CO 2 was also possible, providing α-hydroxy acids without the isolation of an α-hydroxy silane.