654071-50-8Relevant articles and documents
Multicatalytic processes using diverse transition metals for the synthesis of alkenes
Lebel, Helene,Paquet, Valrie
, p. 11152 - 11153 (2007/10/03)
A series of cascade processes for the synthesis of alkenes from alcohols is described. Each individual step is catalyzed with a specific transition metal complex. The oxidation-methylenation one-pot procedure took place in the presence of a palladium and a rhodium catalyst to produce the desired terminal alkenes in high yields. A methylenation-ring-closing metathesis allowed the synthesis of cyclic alkenes from carbonyl derivatives, using the second-generation metathesis catalyst. Finally, an oxidation-methylenation-RCM process that involves up to three different transition metal catalysts in the same vessel is presented. Copyright
Tandem Michael/intramolecular aldol reactions mediated by secondary amines, thiols and phosphines
Dinon, Franceses,Richards, Elinor,Murphy, Patrick J.,Hibbs, David E.,Hursthouse, Michael B.,Malik, K. M. Abdul
, p. 3279 - 3282 (2007/10/03)
The secondary amine mediated Baylis-Hillman reaction has been found to proceed via a tandem Michael addition/intramolecular aldol followed by a slow elimination step; it was also observed that similar processes can be effected using phosphines and thiols as mediators.
