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65495-21-8

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65495-21-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 65495-21-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,4,9 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 65495-21:
(7*6)+(6*5)+(5*4)+(4*9)+(3*5)+(2*2)+(1*1)=148
148 % 10 = 8
So 65495-21-8 is a valid CAS Registry Number.

65495-21-8Relevant articles and documents

Synthesis and oxidation-induced DNA cross-linking capabilities of bis(catechol) quaternary ammonium derivatives

Song, Zhibin,Weng, Xiaocheng,Weng, Liwei,Huang, Jing,Wang, Xiaolin,Bai, Minghui,Zhou, Yangyang,Yang, Guangfu,Zhou, Xiang

, p. 5751 - 5754 (2008)

A study was conducted to demonstrate the synthesis of a number of DNA crosslinking agents, such as bis(catechol) quaternary ammonium derives. It was found that these agents can crosslink DNA through an o-quinone intermediate, induced by oxidation. It was also found that these compounds are composed of two catechol monomers, acting as DNA cross-linking units and are joined by different linkers that act as DNA binding units. Positive charged linkers and quaternary ammonium derivatives were used in the study, to achieve high affinity to DNA. Aliphatic and aromatic chains were investigated, to determine their ability in performing favorable cross-linking reactions and to determine the relationship between agent flexibility and DNA cross-linking abilities.

Synthesis and Structure-Activity Relationships of 3-Arylisoquinolone Analogues as Highly Specific hCES2A Inhibitors

Zhao, Yitian,Xiong, Yuan,Dong, Sanfeng,Guan, Xiaoqing,Song, Yunqing,Yang, Yanqing,Zou, Kun,Li, Zhao,Zhang, Yong,Fang, Shengquan,Li, Bo,Zhu, Weiliang,Chen, Kaixian,Jia, Qi,Ge, Guangbo

, p. 388 - 398 (2020/10/26)

Mammalian carboxylesterases (CES) are key enzymes that participate in the hydrolytic metabolism of various endogenous and exogenous substrates. Human carboxylesterase 2A (hCES2A), mainly distributed in the small intestine and colon, plays a significant ro

Discovery of dihydrooxazolo[2,3-: A] isoquinoliniums as highly specific inhibitors of hCE2

Ding, Lixia,Wang, Lu,Zou, Kun,Li, Bo,Song, Yunqing,Zhang, Qihua,Zhao, Yitian,Xu, Zhijian,Ge, Guangbo,Zhao, Bo,Zhu, Weiliang

, p. 35904 - 35912 (2019/11/16)

Human carboxylesterase 2 (hCE2) is one of the most abundant esterases distributed in human small intestine and colon, which participates in the hydrolysis of a variety of ester-bearing drugs and thereby affects the efficacy of these drugs. Herein, a new c

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