66021-98-5

Basic information

• Product Name: Benzene, 1-methoxy-2-(1-propynyl)-
• CAS NO: 66021-98-5
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• Mol File: 66021-98-5.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-2-(1-propynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-2-(1-propynyl)-(66021-98-5)
• EPA Substance Registry System: Benzene, 1-methoxy-2-(1-propynyl)-(66021-98-5)

Safety Data

• Hazardous Substances Data: 66021-98-5(Hazardous Substances Data)

Upstream product

• 578-57-4 2-bromoanisole 
• 74-99-7 prop-1-yne 
• 579-74-8 2-Methoxyacetophenone 
• 84645-45-4 lithio(trimethylsilyl)diazomethane 
• 14804-32-1 2-ethylanisole 
• 74-88-4 methyl iodide 
• 5211-62-1 1-(2-methoxyphenyl)propan-2-one 
• 135-02-4 ortho-anisaldehyde 
• 19350-70-0 2-methoxybenzaldehyde p-toluenesulfonylhydrazone 
• 74-86-2 acetylene 
• 529-28-2 4-iodoanisol 
• 590-93-2 2-Butynoic acid 
• 767-91-9 1-ethynyl-2-methoxybenzene 
• 58335-31-2 1,3-dilithiopropyne 

Downstream Products

• 2077-35-2 (Z)-1-methoxy-2-(prop-1-en-1-yl)benzene 
• 1235712-62-5 C₁₈H₁₇NO₂ 
• 1235712-63-6 C₁₈H₁₇NO₂ 
• 1400576-24-0 methyl 2-(2-methoxyphenyl)-3-methyl-1-phenylcycloprop-2-ene-1-carboxylate 
• 2077-36-3 (E)-1-(2-methoxyphenyl)prop-1-ene 
• 5293-78-7 2,2'-dimethoxytolane 
• 4265-25-2 2-methylbenzofuran 

Relevant articles and documents

Regio- And stereoselective electrochemical synthesis of sulfonylated enethers from alkynes and sulfonyl hydrazides

An electrooxidative direct difunctionalization of internal alkynes with sulfonyl hydrazides has been developed for the construction of sulfonated enethers. In this transformation, metal catalysts or stoichiometric amount of oxidants are not required and molecular nitrogen and hydrogen are the sole byproducts, providing a simple and green approach for preparing various sulfonyl tetrasubstituted alkenes. Notably, the protocol could be efficiently scaled up and the follow-up procedures of the corresponding functionalized alkenes demonstrate the practicality of the electrochemical synthesis.

Palladium-catalyzed methylation of terminal alkynes

In this communication, a palladium-catalyzed procedure for the methylation of terminal alkynes has been developed. With N,N,N-trimethylbenzenaminium trifluoromethanesulfonate as the methyl source, various desired products were obtained in moderate to good yields. Both aromatic and aliphatic alkynes are applicable.

Regiospecific palladium-catalyzed cross-coupling reactions using the operational equivalent of 1,3-dilithiopropyne

A regiospecific palladium-catalyzed cross-coupling reaction using the operational equivalent of the dianion 1,3-dilithiopropyne, with aromatic iodides is reported. This reaction gives high yields of 1-propyn-1-yl-benzenes and 2-(propyn-1-yl)thiophenes in