677-24-7 Usage
Chemical Description
Methyl phosphorodichloridate is a chemical compound with the formula CH3POCl2.
Description
METHYL PHOSPHORODICHLORIDATE, also known as Methyl dichlorophosphate, is an organophosphorus compound with the chemical formula (CH3O)P(O)Cl2. It is a colorless to pale yellow liquid with a pungent odor and is known for its reactivity and potential applications in various chemical syntheses.
Uses
Used in Pharmaceutical and Chemical Industries:
METHYL PHOSPHORODICHLORIDATE is used as a synthetic intermediate for the production of various compounds, including:
1. 4,6-Cyclic phosphate tetrasaccharide: METHYL PHOSPHORODICHLORIDATE is used as a key intermediate in the synthesis of this complex carbohydrate structure, which has potential applications in the development of new drugs and pharmaceuticals.
2. 8-(2′′-hydroxyethoxy)adenosine-5′,2′′-phosphate derivative: METHYL PHOSPHORODICHLORIDATE, synthesized using METHYL PHOSPHORODICHLORIDATE, has potential applications in the development of new drugs targeting adenosine receptors, which play a role in various physiological processes.
3. Analogs of (R)-1-O-hexadecyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine poly(ethylene glycol): METHYL PHOSPHORODICHLORIDATE is used as a synthetic building block in the creation of these analogs, which may have applications in the development of targeted drug delivery systems.
4. Dioxaphosphorino[m,n-x]pyridines compounds: METHYL PHOSPHORODICHLORIDATE is utilized in the synthesis of these novel heterocyclic compounds, which could have potential applications in the development of new pharmaceuticals and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 677-24-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,7 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 677-24:
(5*6)+(4*7)+(3*7)+(2*2)+(1*4)=87
87 % 10 = 7
So 677-24-7 is a valid CAS Registry Number.
InChI:InChI=1/CH3Cl2O2P/c1-5-6(2,3)4/h1H3
677-24-7Relevant articles and documents
Kluger et al.
, p. 6066,6067 (1969)
The chlorination reaction of O-alkyl S-alkyl(aryl) thiophosphoric(-nic) acid derivatives with phosphorus oxychloride
He, Zheng-Jie,Chen, Wen-Bing,Ma, Fu-Peng,Zhou, Zheng-Hong,Tang, Chu-Chi
, p. 49 - 55 (2007/10/03)
It is reported that a variety of O-alkyl S-alkyl(aryl) thiophosphoric(-nic) acid derivatives 4 can be readily chlorinated with phosphorus oxychloride giving S-alkyl(aryl) thiophosphoro(-no)chloridates 2 and O-alkyl phosphorodichloridates 3.
AN IMPROVED SYNTHESIS OF MONOESTERS OF PHOSPHORIC ACID
Modro, Agnes M.,Modro, Tomasz A.
, p. 57 - 60 (2007/10/03)
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