68602-57-3

Basic information

• Product Name: TRIFLUOROACETYL TRIFLATE
• Synonyms: TRIFLUOROMETHYLSULFONYL TRIFLUOROACETATE;TRIFLUOROACETYL TRIFLATE;TRIFLUOROACETYL TRIFLUOROMETHANESULFONATE;TRIFLUOROACETYL TRIFLUOROMETHANESULPHONATE;TRIFLUOROACETIC ACID, ANHYDRIDE WITH TRIFLUOROMETHANESULFONIC ACID;TFAT;TRIFLUOROACETIC ACID, ANHYDRIDE WITH TRI FLUOROMETHANE-SO3H, TECH., 90%;TRIFLUOROACETYLTRIFLATE,90%
• CAS NO: 68602-57-3
• Molecular Formula: C₃F₆O₄S
• Molecular Weight: 246.09
• Mol File: 68602-57-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 62-63 °C(lit.)
• Appearance: /
• Density: 1.8103 (estimate)
• Vapor Pressure: 400 mm Hg ( 21.1 °C)
• Refractive Index: 1.296-1.3
• Storage Temp.: Refrigerator
• CAS DataBase Reference: TRIFLUOROACETYL TRIFLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIFLUOROACETYL TRIFLATE(68602-57-3)
• EPA Substance Registry System: TRIFLUOROACETYL TRIFLATE(68602-57-3)

Safety Data

• Hazard Codes: C,T
• Statements: 20/21/22-34-25
• Safety Statements: 26-27-28-36/37/39-45
• RIDADR: UN 3265 8/PG 1
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 68602-57-3(Hazardous Substances Data)

Usage

Chemical Properties

clear light yellow liquid

Uses

Trifluoroacetic acid, anhydride with trifluoromethanesulfonic acid may be used in chemical synthesis studies.

Safety Profile

Violent reaction with water.When heated to decomposition it emits toxic fumes of F??and SOx.

Upstream product

• 1493-13-6 trifluorormethanesulfonic acid 
• 76-05-1 trifluoroacetic acid 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 115726-23-3 triphenylmethyl trifluoromethanesulfonate 
• 109244-10-2 Trifluoro-acetic acid 2-methyl-cyclohex-1-enyl ester 
• 109244-11-3 Trifluoro-acetic acid 6-methyl-cyclohex-1-enyl ester 
• 383-65-3 N-allyltrifluoroacetamide 
• 1493-13-6 trifluorormethanesulfonic acid 
• 407-25-0 trifluoroacetic anhydride 
• 868162-64-5 Benzoic acid (3S,5S,8R,9S,10S,12R,13S)-3-acetoxy-17-[(1S,2R)-1,5-dimethyl-2-(2,2,2-trifluoro-acetoxy)-hex-5-enyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[a]phenanthren-12-yl ester 
• 1202747-57-6 C₅₁H₆₇F₃O₉Si 
• 1149761-67-0 (1-benzoyl-4-fluoropiperidin-4-yl)methyltrifluoromethanesulfonic acid 
• 1370639-93-2 C₄₇H₆₅F₃O₅Si 
• 1370639-91-0 C₄₇H₆₅F₃O₅Si 
• 1370639-92-1 C₄₇H₆₅F₃O₅Si 
• 1370639-85-2 C₅₆H₆₆F₆O₉Si 
• 1370639-83-0 C₃₈H₄₇F₃O₆ 

Relevant articles and documents

Reactions of the Readily Accessible Electrophile, Trifluoroacetyl Triflate: A Very Reactive Agent for Trifluoroacetylations at Oxygen, Nitrogen, Carbon, or Halogen Centers

Trifluoroacetyl triflate (TFAT) is readily prepared in 82percent yield by the dehydration (phosphorus pentoxide) of a 2:1 mixture of trifluoroacetic acid and trifluoromethanesulfonic (triflic) acid.Reactions of this highly electrophilic trifluoroacetylating reagent with alcohols, ketones, ethers, amines, and pyridines give esters, enol esters, ether cleavage, amides, and acylpyridinium ions, respectively.Reactions with ionic or easily ionizable alkyl halides give the very volatile trifluoroacetyl halides and the ionic triflate.Triphenylmethyl chloride, for example, is quantitatively converted to triphenylcarbenium triflate in a very convenient synthetic procedure.Trifluoroacetyl triflate is used in the synthesis of the first member of a new class of pyrylium salts, 2,6-dimethoxypyrylium triflate.