6876-65-9

Basic information

• Product Name: Benzeneacetamide, N-(4-methylphenyl)-
• CAS NO: 6876-65-9
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 6876-65-9.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: Benzeneacetamide, N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetamide, N-(4-methylphenyl)-(6876-65-9)
• EPA Substance Registry System: Benzeneacetamide, N-(4-methylphenyl)-(6876-65-9)

Safety Data

• Hazardous Substances Data: 6876-65-9(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 106-49-0 p-toluidine 
• 103-81-1 Benzeneacetamide 
• 51463-66-2 dimethyl (2-phenylacetyl)phosphonate 
• 60565-62-0 2-phenyl-1-(p-tolyl)ethan-1-one tosylhydrazone 
• 103-80-0 phenylacetyl chloride 
• 16979-20-7 N-(4-methylbenzylidene)-4-methylaniline 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 681455-21-0 N-[1-(benzotriazol-1-yl)-2-phenylethylidene]-4-methylaniline 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 30516-21-3 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylethan-1-one 
• 110915-73-6 anhydride N-acetyl phenyl-acetohydroxamique-acetique 
• 5720-05-8 4-methylphenylboronic acid 
• 31614-66-1 tributyl(p-tolyl)stannane 

Downstream Products

• 90362-96-2 6-methyl-2-(phenylmethyl)-4(3H)-quinazolinone 
• 681455-21-0 N-[1-(benzotriazol-1-yl)-2-phenylethylidene]-4-methylaniline 
• 934495-95-1 2-phenyl-N-p-tolyl-acetimidoyl chloride 
• 73108-78-8 6-methyl-3-phenylquinolin-2(1H)-one 
• 1253778-98-1 2-phenyl-N-(4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl)acetamide 
• 19711-87-6 2-oxo-2-diphenyl-N-(p-tolyl)acetamide 
• 103-81-1 Benzeneacetamide 

Relevant articles and documents

Metal-free transamidation of benzoylpyrrolidin-2-one and amines under aqueous conditions

N-Acyl lactam amides, such as benzoylpyrrolidin-2-one, benzoylpiperidin-2-one, and benzoylazepan-2-one reacted with amines in the presence of DTBP and TBAI to afford the transamidated products in good yields. The reactions were conducted under aqueous conditions and good functional group tolerance was achieved. Both aliphatic and aromatic primary amines displayed good activity under metal-free conditions. A radical reaction pathway is proposed.

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.

Copper-Catalyzed Coupling Reaction of (Hetero)Aryl Chlorides and Amides

Cu2O/N,N′-bis(thiophen-2-ylmethyl)oxalamide is established to be an effective catalyst system for Goldberg amidation with inferior reactive (hetero)aryl chlorides, which have not been efficiently documented by Cu-catalysis to date. The reaction is well liberalized toward a variety of functionalized (hetero)aryl chlorides and a wide range of aromatic and aliphatic primary amides in good to excellent yields. Furthermore, the arylation of lactams and oxazolidinones is achieved. The present catalytic system also accomplished an intramolecular cross-coupling product.