7032-11-3 Usage
Description
1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXAMIDE, with the molecular formula C7H11N3O, is an amide derivative of pyridine. It is a chemical compound that has garnered significant interest in pharmaceutical research and development due to its potential applications in medicine and healthcare.
Uses
Used in Pharmaceutical Research and Development:
1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXAMIDE is used as a chemical compound in pharmaceutical research and development for its potential as an antitumor agent. It has been studied for its ability to inhibit the growth of cancer cells, making it a promising candidate for cancer treatment.
Used in Oncology:
In the field of oncology, 1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXAMIDE is used as a potential antitumor agent for its ability to inhibit the growth of various types of cancer cells. Its effectiveness in targeting cancer cells without harming healthy cells is a key area of research.
Used in Neurodegenerative Disease Treatment:
1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXAMIDE is also being researched for its potential as a treatment for neurodegenerative diseases such as Alzheimer's and Parkinson's. Its role in potentially slowing down or managing the progression of these diseases is an important focus of ongoing studies.
Overall, 1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXAMIDE is a versatile chemical compound with significant potential in various medical applications, particularly in the areas of oncology and neurodegenerative disease treatment. Its continued research and development are crucial for unlocking its full potential in healthcare.
Check Digit Verification of cas no
The CAS Registry Mumber 7032-11-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,0,3 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7032-11:
(6*7)+(5*0)+(4*3)+(3*2)+(2*1)+(1*1)=63
63 % 10 = 3
So 7032-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H10N2O/c7-6(9)5-2-1-3-8-4-5/h4-5H,1-3H2,(H2,7,9)/t5-/m1/s1
7032-11-3Relevant articles and documents
Development and Scale-Up of an Asymmetric Synthesis Process for Alogliptin
Yamada, Masatoshi,Hirano, Sayuri,Tsuruoka, Ryoji,Takasuga, Masahiro,Uno, Kenichi,Yamaguchi, Kotaro,Yamano, Mitsuhisa
, p. 327 - 336 (2021/03/01)
Alogliptin (1) benzoate is a potent, highly selective inhibitor of serine protease dipeptidyl-peptidase IV, approved by US FDA for the treatment of type 2 diabetes. Herein, we report a more cost-effective process that includes ruthenium-catalyzed asymmetric hydrogenation followed by Hofmann rearrangement of 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile (10) to introduce a chiral amino moiety at a late stage. Use of an inexpensive and readily available nicotinamide (6) for a chiral aminopiperidine core and iodobenzene diacetate (PIDA) under mild and specific conditions allowed us to access 1 with excellent total yield and comparable quality to that manufactured by the original process.
Tetrahydropyridines.
Wenkert,Dave,Haglid,Lewis,Oishi,Stevens,Terashima
, p. 747 - 753 (2007/10/04)
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