71298-03-8Relevant articles and documents
Chemo- and regioselective preparation of zinc enolate from thiol esters by palladium catalyzed cross-coupling reaction
Haraguchi, Ryosuke,Ikeda, Zenichi,Ooguri, Akihiro,Matsubara, Seijiro
, p. 8830 - 8837 (2015/10/20)
The palladium catalyzed cross-coupling reaction of thiol esters with bis(iodozincio)methane or 1,1-bis(iodozincio)ethane gave Reformatsky-type enolates. They can react with some electrophiles to give the corresponding adducts and were also trapped by silylation reagents to afford silyl enol ethers. As the method applicable to the thiol ester carrying ketone moiety, it afforded zinc enolates carrying ketone in the same molecule.
Chemo- and regioselective preparation and reaction of a kinetic zinc enolate formed from a thiol ester and bis(iodozincio)methane
Ikeda, Zenichi,Hirayama, Takaharu,Matsubara, Seijiro
, p. 8200 - 8203 (2007/10/03)
(Chemical Equation Presented) Reactive functionalized enolates that are otherwise difficult to obtain can be prepared in a simple procedure by the treatment of a thiol ester with bis(iodozincio)methane in the presence of a palladium catalyst (see scheme). The terminal zinc enolates thus formed are kinetically controlled and react with a variety of electrophiles, such as aldehydes, ketones, and acyl cyanides. FG = functional group.