731798-31-5

Basic information

• Product Name: Benzamide, 3,4,5-trimethoxy-N-[(3S)-tetrahydro-2,6-dioxo-2H-pyran-3-yl]-
• CAS NO: 731798-31-5
• Molecular Formula: C15H17NO7
• Molecular Weight: 323.302
• Mol File: 731798-31-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzamide, 3,4,5-trimethoxy-N-[(3S)-tetrahydro-2,6-dioxo-2H-pyran-3-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 3,4,5-trimethoxy-N-[(3S)-tetrahydro-2,6-dioxo-2H-pyran-3-yl]-(731798-31-5)
• EPA Substance Registry System: Benzamide, 3,4,5-trimethoxy-N-[(3S)-tetrahydro-2,6-dioxo-2H-pyran-3-yl]-(731798-31-5)

Safety Data

• Hazardous Substances Data: 731798-31-5(Hazardous Substances Data)

Upstream product

• 35455-36-8 (S)-2-(3,4,5-trimethoxybenzamido)pentanedioic acid 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 118-41-2 Eudesmic acid 

Downstream Products

• 942123-68-4 (S)-2-(2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetic acid 

Relevant articles and documents

Novel aminopeptidase N inhibitors derived from antineoplaston AS2-5 (Part I)

Overexpression of zinc-dependent metalloproteinase, aminopeptidase N (APN/CD13), is considered to be involved in the process of tumor invasion and metastasis. Herein we describe the synthesis and in vitro enzymatic inhibition assay of antineoplaston AS2-5 scaffold peptidomimetic compounds. The results demonstrated that most of these l-iso-glutamine derivatives displayed selective inhibitory activity against APN as compared with MMP-2, with IC50 values in the micromole range. The structure-activity relationships were also briefly discussed.

Novel 3-galloylamido-N′-substituted-2,6-piperidinedione-N-acetamide peptidomimetics as metalloproteinase inhibitors

Both of aminopeptidase N (APN) and matrix metalloproteinase (MMP) are essential metallopeptidases in the development of tumor invasion and angiogenesis. Novel potent peptidomimetic inhibitors, containing 3-galloylamido-N′-substituted-2,6-piperidinedione-N