7403-40-9

Basic information

• Product Name: 2,2-dichloro-N-(4-chlorophenyl)acetamide
• CAS NO: 7403-40-9
• Molecular Formula: C₈H₆Cl₃NO
• Molecular Weight: 238.4983
• Mol File: 7403-40-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 371.1°C at 760 mmHg
• Flash Point: 178.3°C
• Density: 1.513g/cm³
• Vapor Pressure: 1.05E-05mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 2,2-dichloro-N-(4-chlorophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dichloro-N-(4-chlorophenyl)acetamide(7403-40-9)
• EPA Substance Registry System: 2,2-dichloro-N-(4-chlorophenyl)acetamide(7403-40-9)

Safety Data

• Hazardous Substances Data: 7403-40-9(Hazardous Substances Data)

Usage

Chemical Class

Amide compounds

Primary Use

Herbicide

Application

Controlling weeds in agricultural fields, particularly in rice paddies

Mechanism of Action

Inhibits chlorophyll synthesis in susceptible plants, leading to plant death

Hazards

Can be harmful to humans and the environment if not properly managed

Environmental Concerns

Potential for groundwater contamination and harmful effects on aquatic organisms

Regulation

Regulated in some countries due to its potential negative environmental effects

Upstream product

• 106-47-8 4-chloro-aniline 
• 198067-01-5 1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloro-1-ethanone 
• 101-92-8 4'-Chloroacetoacetanilide 
• 79-43-6 dichloro-acetic acid 
• 79-36-7 dichloroacethyl chloride 

Relevant articles and documents

An Efficient Greener Approach for N-acylation of Amines in Water Using Benzotriazole Chemistry

A straightforward, mild and cost-efficient synthesis of various arylamides in water was accomplished using versatile benzotriazole chemistry. Acylation of various amines was achieved in water at room temperature as well as under microwave irradiation. The developed protocol unfolds the synthesis of amino acid aryl amides, drug conjugates and benzimidazoles. The environmentally friendly synthesis, short reaction time, simple workup, high yields, mild conditions and free of racemization are the key advantages of this protocol.

Approach for the direct synthesis of β-dichlorosubstituted acetanilides using iodine trichloride (ICl3) as the oxidant and catalyst

A reliable method for direct synthesis of β-dichlorosubstituted acetanilides is reported. The key transformation involves the oxidative and catalytic cleavage of a carbon-carbon bond in the presence of iodine trichloride (ICl3). In this protoco

Organic synthesis using (diacetoxyiodo)benzene (DIB): Unexpected and novel oxidation of 3-oxobutanamides to 2,2-dihalo-N-phenylacetamides

A novel and reliable method for the direct preparation of 2,2-dihalo-N-phenylacetamides is reported. The key transformation involves the cleavage of a carbon-carbon bond in the presence of DIB and a Lewis acid as the halogen source, and thus this method s