74641-60-4Relevant articles and documents
Probing the nuclear susceptibility of mesoionic compounds using two-beam coupling with chirp-controlled pulses
Bosco, Carlos A.C.,Maciel, Glauco S.,Rakov, Nikifor,de Araújo, Cid B.,Acioli, Lúcio H.,Simas, Alfredo M.,Athayde-Filho, Petr?nio F.,Miller, Joseph
, p. 101 - 106 (2007)
The third-order non-linear optical response of mesoionic compounds (MIC) in dimethylsulfoxide (DMSO) and methanol solutions was investigated by use of collinear pump and probe technique with chirp-controlled femtosecond pulses. The experiments allowed the investigation of non-instantaneous nuclear processes and thermal effects induced by two-photon absorption (TPA). We found that the nuclear non-linearity of MIC in DMSO is ~1/5 the benzene, which was used as a reference material. This result is attributed to the large inertia of MIC to rotation, compared to benzene. The results for MIC in methanol indicate the influence of thermal effects due to TPA.
Phosphinamide-directed benzylic lithiation. application to the synthesis of peptide building blocks
Burgos, Pascual Ona,Fernandez, Ignacio,Iglesias, Maria Jose,Garcia-Granda, Santiago,Ortiz, Fernando Lopez
, p. 537 - 540 (2008/04/05)
N-Benzyldiphenylphosphinamides are deprotonated at the NCα position diastereospecifically upon treatment with f-BuLi in diethyl ether at low temperature. The reaction of the anions with alkyl, acyl, and tin halides, aliphatic and aromatic aldehydes, and Michael acceptors allowed installation of a variety of functional groups into the benzylic arm in excellent yields. Cleavage of the P-N linkage affords 1,2-amino alcohols and α-, β-, and γ-amino acids.
Synthesis and utilization of a novel glycine derived chiral precursor, based on a recyclable L-prolinol auxiliary, for the enantioselective preparation of α-amino acids and their N-methyl derivatives
Pandey,Reddy,Das
, p. 3175 - 3178 (2007/10/03)
α-Amino acids and their N-methyl derivatives are synthesized in fairly high optical purity employing a new glycine derived template based on a recyclable L-prolinol chiral auxiliary.