7499-20-9

Basic information

• Product Name: hept-2-yn-1-ylpropanedioic acid
• CAS NO: 7499-20-9
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 198.2158
• Mol File: 7499-20-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 377.5°C at 760 mmHg
• Flash Point: 196.3°C
• Density: 1.19g/cm³
• Vapor Pressure: 9.66E-07mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: hept-2-yn-1-ylpropanedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: hept-2-yn-1-ylpropanedioic acid(7499-20-9)
• EPA Substance Registry System: hept-2-yn-1-ylpropanedioic acid(7499-20-9)

Safety Data

• Hazardous Substances Data: 7499-20-9(Hazardous Substances Data)

Upstream product

• 92372-61-7 Ethyl-2-carbethoxynon-4-yn-1-oate 
• 1002-36-4 hep-2-yn-1-ol 
• 18495-26-6 1-bromo-2-heptyne 
• 105-53-3 diethyl malonate 
• 110460-54-3 hept-2-ynyl-trimethyl-ammonium; iodide 

Downstream Products

• 20731-15-1 Nonin-(4)-saeuremethylester 

Relevant articles and documents

Catalytic asymmetric protonation of chiral calcium enolates via 1,4-addition of malonates

Catalytic asymmetric protonation of chiral calcium enolates was performed. Chiral calcium enolates, prepared in situ from imides and malonates via 1,4-addition in the presence of catalytic amounts of Ca(OEt)2, Ph-PyBox, and achiral phenol, were smoothly protonated to afford adducts bearing tertiary asymmetric carbons in high yields with high enantioselectivities. The adducts were readily converted to optically active 2-substituted 1,5-dicarboxylic acid derivatives.