75105-08-7

Basic information

• Product Name: C₁₁H₁₆N₂S
• Synonyms: C₁₁H₁₆N₂S
• CAS NO: 75105-08-7
• Molecular Weight: 208.327
• Mol File: 75105-08-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₆N₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₆N₂S(75105-08-7)
• EPA Substance Registry System: C₁₁H₁₆N₂S(75105-08-7)

Safety Data

• Hazardous Substances Data: 75105-08-7(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 614-69-7 2-tolyl isothiocyanate 

Downstream Products

• 1029435-58-2 (2Z,5Z)-5-[(3-chloro-4-hydroxyphenyl)methylene]-3-(o-tolyl)-2-propyliminothiazolidin-4-one 
• 854111-49-2 Ponesimod 
• 854107-53-2 (Z)-2-propylimino-3-(2-methylphenyl)thiazolidin-4-one 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF|(2Z,5Z)-5-(3-CHLORO-4-((R)-2,3-DIHYDROXYPROPOXY)BENZYLIDENE)-2-(PROPYLIMINO)-3-|(O-TOLYL)THIAZOLIDIN-4-ONE AND INTERMEDIATE USED IN SAID PROCESS

The present invention relates to a new process for the preparation of (2Z,5Z)-5-(3-chloro-4- ((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and to the new intermediate (R)-3-chloro-4-(2,3-dihydroxypropoxy)-benzaldehyde used in this process. (2Z,5Z)-5-(3-Chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3- (o-tolyl)thiazolidin-4-one is described in WO 2005/054215 to act as an immunosuppressive agent. The present invention further also relates to a new process for the preparation of (R)-3-chloro-4-(2,3-dihydroxypropoxy)-benzaldehyde.