766-96-1 Usage
Description
4-Bromophenylacetylene, also known as 1-Bromo-4-ethynylbenzene, is an organic compound characterized by the presence of a bromine atom attached to a phenyl ring and an acetylene functional group. This unique structure endows it with specific chemical properties that make it a versatile building block in various synthetic applications.
Uses
Used in the Synthesis of Advanced Materials:
4-Bromophenylacetylene is used as a starting material for the development of second-order nonlinear optical materials. These materials exhibit the ability to manipulate light at the molecular level, which is crucial for applications in optoelectronics, photonics, and advanced communication technologies.
Used in the Formation of Heterocyclotriynes:
4-Bromophenylacetylene is also utilized in the synthesis of heterocyclotriynes, which are valuable intermediates in organic chemistry. Heterocyclotriynes are known for their ability to form stable complexes with transition metals, making them useful in the creation of novel coordination compounds and catalysts.
Used in the Production of Unsymmetrical 1,4-Diarylbutadiynes:
4-Bromophenylacetylene serves as a key component in the preparation of unsymmetrical 1,4-diarylbutadiynes. These organic molecules are of interest in materials science due to their potential use in the development of new polymers and organic semiconductors.
Used in Organic Synthesis:
In the specific case of 1-bromo-4-(4′-tetrahydropyranyloxy-1′-ethynylphenyl)benzene synthesis, 1-Bromo-4-ethynylbenzene is used as a precursor. 4-Bromophenylacetylene is an example of how 4-Bromophenylacetylene can be employed in the synthesis of complex organic molecules for various applications, including pharmaceuticals and specialty chemicals.
Synthesis Reference(s)
The Journal of Organic Chemistry, 54, p. 3224, 1989 DOI: 10.1021/jo00274a055Tetrahedron, 62, p. 6673, 2006 DOI: 10.1016/j.tet.2005.12.077
Check Digit Verification of cas no
The CAS Registry Mumber 766-96-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,6 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 766-96:
(5*7)+(4*6)+(3*6)+(2*9)+(1*6)=101
101 % 10 = 1
So 766-96-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H5Br/c1-2-7-3-5-8(9)6-4-7/h1,3-6H
766-96-1Relevant articles and documents
Synthesis of alkynes under dry reaction conditions
Rao, Maddali L.N.,Shamim Islam, Sk
supporting information, (2021/04/19)
An easy synthetic method was developed under dry reaction conditions for the preparation of terminal alkynes from 1,1-dibromoalkenes and in the presence of succinimide which acts as a nucleophile and proton donor. It was demonstrated with the synthesis of a broad spectrum of terminal alkynes and extended to synthesize internal alkynes under tandem reaction conditions.
Synthesis and Photochemical Application of Hydrofluoroolefin (HFO) Based Fluoroalkyl Building Block
Varga, Bálint,Tóth, Balázs L.,Béke, Ferenc,Csenki, János T.,Kotschy, András,Novák, Zoltán
, p. 4925 - 4929 (2021/07/01)
A novel fluoroalkyl iodide was synthesized on multigram scale from refrigerant gas HFO-1234yf as cheap industrial starting material in a simple, solvent-free, and easily scalable process. We demonstrated its applicability in a metal-free photocatalytic ATRA reaction to synthesize valuable fluoroalkylated vinyl iodides and proved the straightforward transformability of the products in cross-coupling chemistry to obtain conjugated systems.
BIPHENYL COMPOUNDS AS SOCE MODULATORS, COMPOSITIONS AND USES THEREOF
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Page/Page column 30; 34, (2021/08/27)
Compound of formula (I) able to modulate Store Operated Calcium Entry (SOCE). The disclosure also relates to compositions and uses of compounds of formula (I) for treatment of disease condition depending on increased/ decreased activity of SOCE.
