76756-47-3

Basic information

• Product Name: 3-benzyl-4-methylthiazolium tetrafluoroborate
• Synonyms: 3-benzyl-4-methylthiazolium tetrafluoroborate
• CAS NO: 76756-47-3
• Molecular Weight: 277.094
• Mol File: 76756-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyl-4-methylthiazolium tetrafluoroborate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-4-methylthiazolium tetrafluoroborate(76756-47-3)
• EPA Substance Registry System: 3-benzyl-4-methylthiazolium tetrafluoroborate(76756-47-3)

Safety Data

• Hazardous Substances Data: 76756-47-3(Hazardous Substances Data)

Upstream product

• 693-95-8 4-Methylthiazole 
• 100-39-0 benzyl bromide 
• 4356-66-5 3-Benzyl-4-methylthiazolium bromide 

Downstream Products

• 100-53-8 phenylmethanethiol 
• 136918-14-4 phthalimide 
• 70625-09-1 3-benzyl-4-methyl-2-phenylsulfanyl-thiazolium; tetrafluoroborate 

Relevant articles and documents

α-Keto Acid Dehydrogenases: A Chemical Model

A model system for the involvement of lipoic acid in α-keto acid dehydrogenase systems is described. 2-(α-Hydroxyethyl)-3-benzyl-4-methylthiazolium tetrafluoroborate (6) serves as precursor for an analogue of the thiamine-bound active aldehyde 1 in the natural system.The model active aldehyde 7 reacts with linear disulfides, yielding thiols and thioesters.The 1,2-dithiolane, methyl lipoate (14), is unreactive under model reaction conditions.The tetrahedral intermediate which would be formed from methyl lipoate (14) plus an active aldehyde analogue 19 has been generated in a nonbiomimetic fashion.The synthetic tetrahedral intermediate 17 undergoes the reverse of the biological, disulfide reductive cleavage reaction.