7699-79-8

Basic information

• Product Name: N-(diphenylmethylidene)-1-phenylmethanamine
• Synonyms: Benzenemethanamine, N- (diphenylmethylene)-; Benzenemethanamine, N-(diphenylmethylene)-; Benzylamine, N- (diphenylmethylene)-
• CAS NO: 7699-79-8
• Molecular Formula: C₂₀H₁₇N
• Molecular Weight: 271.3557
• Mol File: 7699-79-8.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 389.7°C at 760 mmHg
• Flash Point: 181.9°C
• Density: 0.99g/cm³
• Vapor Pressure: 6.27E-06mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: N-(diphenylmethylidene)-1-phenylmethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(diphenylmethylidene)-1-phenylmethanamine(7699-79-8)
• EPA Substance Registry System: N-(diphenylmethylidene)-1-phenylmethanamine(7699-79-8)

Safety Data

• Hazardous Substances Data: 7699-79-8(Hazardous Substances Data)

Usage

Description

N-(diphenylmethylidene)-1-phenylmethanamine, commonly known as Benzhydrylamine, is a chemical compound characterized by its molecular formula C26H21N. It presents as a white to off-white crystalline solid with a molecular weight of 335.444 g/mol. Benzhydrylamine is recognized for its role as an intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and agrochemical industries.

Uses

Used in Pharmaceutical Industry:
Benzhydrylamine is utilized as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the formation of complex organic molecules that can have medicinal properties.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, Benzhydrylamine serves as a precursor in the production of compounds that can be used in the development of pesticides and other agricultural chemicals.
Used in Chemical Industry for Dyes and Pigments:
Benzhydrylamine is also employed in the chemical industry for the production of dyes and pigments, where its chemical structure allows for the creation of a variety of colorants used in different applications.
Used in the Production of Other Industrial Chemicals:
Its versatility extends to other areas within the chemical industry, where Benzhydrylamine is used in the synthesis of a range of industrial chemicals, highlighting its importance as a building block in chemical manufacturing processes.

Upstream product

• 110-86-1 pyridine 
• 2051-90-3 Dichlorodiphenylmethane 
• 100-46-9 benzylamine 
• 62506-88-1 N-benzylidenediphenylmethanamine 
• 141-52-6 sodium ethanolate 
• 36728-39-9 N-(α-benzylamino-benzhydryl)-propionamide 
• 119-61-9 benzophenone 
• 18406-59-2 N-benzyl-N,N-bis(trimethylsilyl)amine 
• 13261-62-6 N,N-dimethyl-2-aminofluorene 
• 140-29-4 phenylacetonitrile 
• 62506-88-1 (E)-N-(phenylmethylene)benzhydrylamine 
• 101370-75-6 1-Benzyl-4-methyl-5,5-diphenyl-4,5-dihydro-1H-tetrazole 
• 2235-01-0 dimethoxydiphenylmethane 
• 100-52-7 benzaldehyde 

Downstream Products

• 62506-88-1 N-benzylidenediphenylmethanamine 
• 119-61-9 benzophenone 
• 103-67-3 benzyl-methyl-amine 
• 107590-85-2 1-Phenyl-hex-3-ynylamine 
• 110321-80-7 6-(Benzhydrylidene-amino)-2,2-dimethyl-5,6-diphenyl-hexan-3-one 
• 97625-65-5 N¹-Benzhydrylidene-1,N²-diphenyl-2-p-tolyl-ethane-1,2-diamine 
• 140-29-4 phenylacetonitrile 
• 13261-62-6 N,N-dimethyl-2-aminofluorene 
• 101-97-3 Ethyl 2-phenylethanoate 
• 106727-49-5 3-benzyl-3,4-dihydro-2,2-diphenyl-2H-1,3-oxazin-4-one 
• 105602-10-6 (Z)-3-(1-Benzyl-4-oxo-2,2-diphenyl-azetidin-3-ylamino)-but-2-enoic acid ethyl ester 
• 97625-62-2 N-Benzhydrylidene-1,2,N'-triphenyl-ethane-1,2-diamine 
• 97625-68-8 N-Benzhydrylidene-N'-(4-methoxy-phenyl)-1,2-diphenyl-ethane-1,2-diamine 
• 108860-22-6 4-(benzoyloxy)-1,1,3,4-tetraphenyl-2-azabuta-1,3-diene 

Relevant articles and documents

Base-Catalyzed [3 + 2] Cycloaddition of N-Benzyl Ketimines to Arylacetylenes Followed by Oxidation: A One-Pot Access to Polyarylated 2 H-Pyrroles via Intermediate Pyrrolines

N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in the KOBut/DMSO solution to 2,3,5-triarylpyrrolines, which are oxidized (chloranil, DDQ) in situ to 2,3,5-triaryl-2H-pyrroles in 53-71% yields. The intermediate 1-pyrrolines can be isolated in 31-91% yields and separately oxidized to the corresponding 2H-pyrroles.

Palladium-Catalyzed Diarylation of Isocyanides with Tetraarylleads for the Selective Synthesis of Imines and α-Diimines

Using tetraaryllead compounds (PbAr4) as arylating reagents, isocyanides undergo selective diarylation in the presence of palladium catalysts such as Pd(OAc)2 or Pd(PPh3)4 to afford imines and/or α-diimines based on the isocyanide employed. With aliphatic isocyanides, imines are obtained preferentially, whereas α-diimines are formed in the case of electron-rich aromatic isocyanides. The differences in imine/α-diimine selectivity can be attributed to the stability of imidoylpalladium intermediates formed in this catalytic reaction. Compared with other arylating reagents, tetraaryllead compounds are excellent candidates for use in the selective transformations to imines and/or α-diimines, especially in terms of inhibiting the oligomerization of isocyanides, which results in a lower product selectivity in many transition-metal-catalyzed reactions of isocyanides.

Visible-Light-Mediated Umpolung Reactivity of Imines: Ketimine Reductions with Cy2NMe and Water

A novel carbanionic reactivity of imines mediated by photoredox catalysis is demonstrated. The umpolung imine reactivity is exemplified by proton abstraction from water as a key step in the reduction of benzophenone ketimines to amines (up to 98% yield). Deuterium is introduced into amines efficiently using D2O as an inexpensive deuterium source (≥95% D ratio). The mechanism of this unusual transformation is probed.