77740-83-1

Basic information

• Product Name: 3-amino-4-chlorobenzaldehyde
• CAS NO: 77740-83-1
• Molecular Formula: C₇H₆ClNO
• Molecular Weight: 155.5816
• Mol File: 77740-83-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 284.1°C at 760 mmHg
• Flash Point: 125.6°C
• Density: 1.348g/cm³
• Vapor Pressure: 0.00304mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 3-amino-4-chlorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-4-chlorobenzaldehyde(77740-83-1)
• EPA Substance Registry System: 3-amino-4-chlorobenzaldehyde(77740-83-1)

Safety Data

• Hazardous Substances Data: 77740-83-1(Hazardous Substances Data)

Usage

General Description

3-amino-4-chlorobenzaldehyde, also known as 3-acetyl-4-hydroxy-2-methyl-2H-1,4-benzoxazine-3-carboxylic acid, is a chemical compound with the molecular formula C7H6ClNO. It is a white to light yellow crystalline powder that is commonly used in the production of pharmaceuticals and agrochemicals. 3-amino-4-chlorobenzaldehyde is also employed as an intermediate in the synthesis of various organic compounds, and it exhibits a range of biological activities, including antibacterial and antifungal properties. Its chemical structure contains an amino group and a chlorobenzene ring, contributing to its versatility and usefulness in various industrial applications. Additionally, 3-amino-4-chlorobenzaldehyde is considered to be relatively stable under normal conditions and is not known to pose significant health or environmental hazards.

Upstream product

• 16588-34-4 4-chloro-3-nitro-benzaldehyde 

Downstream Products

• 1025772-13-7 N-(2-chloro-5-formylphenyl)-5-methylisoxazole-3-carboxamide 
• 714951-29-8 9-(3-bromo-4-chlorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide 
• 1709-44-0 m-aminobenzaldehyde 

Relevant articles and documents

Simple and Practical Synthesis of Various New Nickel Boride-Based Nanocomposites and their Applications for the Green and Expeditious Reduction of Nitroarenes to Arylamines under Wet-Solvent-Free Mechanochemical Grinding

In this paper, we report a simple synthesis of four new nickel boride-based nanocomposites, namely Ni2B@ZrCl4, Ni2B@Cu2O, Ni2B@CuCl2 and Ni2B@FeCl3, from commercially available and cheap starting materials. All of the new Ni2B-based nanocomposites were well characterized by Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. Further, the catalytic applications of these new nanocomposites were successfully evaluated in the wet-solvent-free reduction of aromatic nitro compounds to arylamines with sodium borohydride (NaBH4) at room temperature by a mechanochemical grinding technique. All the introduced catalytic systems provide excellent yields of arylamines in very short reaction times for a wide range of substrates. Also, recoverability and reusability of the new nanocomposites were investigated.

Chemo- and regioselective reduction of nitroarenes, carbonyls and azo dyes over nickel-incorporated hexagonal mesoporous aluminophosphate molecular sieves

Nickel-incorporated hexagonal mesoporous aluminophosphate (NiHMA) molecular sieves were found to be highly efficient heterogeneous catalysts for the chemo- and regioselective reduction of nitroarenes and carbonyl compounds as well as the reductive cleavage of azo functions, including bulkier substrates, by the hydrogen transfer method.

Pyrano, piperidino, and thiopyrano compounds and methods of use

The present invention provides novel compounds of formula I which may be useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions.