78215-79-9

Basic information

• Product Name: 2-phenyl-1,3,2-oxazaphosphole-2-oxide
• Synonyms: 2-phenyl-1,3,2-oxazaphosphole-2-oxide
• CAS NO: 78215-79-9
• Molecular Weight: 223.211
• Mol File: 78215-79-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-phenyl-1,3,2-oxazaphosphole-2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-1,3,2-oxazaphosphole-2-oxide(78215-79-9)
• EPA Substance Registry System: 2-phenyl-1,3,2-oxazaphosphole-2-oxide(78215-79-9)

Safety Data

• Hazardous Substances Data: 78215-79-9(Hazardous Substances Data)

Upstream product

• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 

Downstream Products

• 69423-57-0 (-)-(S)_p methyl ethylphosphinate 
• 61733-60-6 (S)-O-ethyl O-methyl phenylphosphonothioate 
• 77929-22-7 (R)-(-)-[O-methyl (o-anisyl)phenylphosphinate] 
• 78177-46-5 (S)-(2-Hydroxymethyl-pyrrolidin-1-yl)-phenyl-phosphinic acid methyl ester 

Relevant articles and documents

4-Dimethylaminopyridine-catalyzed dynamic kinetic resolution in asymmetric synthesis of P-chirogenic 1,3,2-oxazaphospholidine-2-oxides

Excellent diastereoselectivity (dr value up to 100: 0) was achieved in DMAP-catalyzed P-N bond formation in the synthesis of P-chirogenic organophosphines from phenylphosphonic dichloride (PhP(O)Cl2) and (S)-2-pyrrolidinemethanol derivatives. I

Enantioselective reduction of ketones by borane catalysed by oxazaphospholidine oxides

New enantioselective catalysts for the asymmetric reduction of ketones by borane are described. Easily prepared by oxidation of chiral oxazaphospholidines, these compounds increase sensitively the reduction rate of numerous ketones and induce ee's up to 94% in the case of the 2-chloroacetophenone.