783331-24-8Relevant articles and documents
An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA α5 receptors with cognition enhancing properties
Chambers, Mark S.,Atack, John R.,Carling, Robert W.,Collinson, Neil,Cook, Susan M.,Dawson, Gerard R.,Ferris, Pushpindar,Hobbs, Sarah C.,O'Connor, Desmond,Marshall, George,Rycroft,MacLeod, Angus M.
, p. 5829 - 5832 (2007/10/03)
(3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2, 4-triazol-5-ylmethoxy)pyrazolo[1,5-d][1,2,4]triazine (13) has been identified as a functionally selective, inverse agonist at the benzodiazepine site of GABAA α5 receptors. 13 is orall