80-06-8

Basic information

• Product Name: 4,4'-DICHLORO-ALPHA-METHYLBENZHYDROL
• Synonyms: 1,1-Bis(4-chlorphenyl)-aethanol;1,1-bis(p-chlorophenyl)-ethano;1,1-Bis(p-Chlorophenyl)ethanol;1,1-Bis(p-chlorophenyl)methylcarbinol;1,1-Bis(p-chorophenyl)ethanol;4,4’-dichloro-(methylbenzhydrol);4,4’-dichloro-alpha-methyl-benzhydro;4,4’-dichloro-alpha-methylbenzohydrol
• CAS NO: 80-06-8
• Molecular Formula: C₁₄H₁₂Cl₂O
• Molecular Weight: 267.15
• EINECS: 201-246-3
• Mol File: 80-06-8.mol
• Article Data: 14

Chemical Properties

• Melting Point: 69-71°C
• Boiling Point: 386.5±32.0 °C(Predicted)
• Appearance: /
• Density: 1.2479 (estimate)
• Storage Temp.: 2-8°C
• PKA: 13.21±0.29(Predicted)
• CAS DataBase Reference: 4,4'-DICHLORO-ALPHA-METHYLBENZHYDROL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DICHLORO-ALPHA-METHYLBENZHYDROL(80-06-8)
• EPA Substance Registry System: 4,4'-DICHLORO-ALPHA-METHYLBENZHYDROL(80-06-8)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-51/53
• Safety Statements: 22-36/37/39-61-36
• RIDADR: 2811
• RTECS: DC7875000
• Hazardous Substances Data: 80-06-8(Hazardous Substances Data)

Usage

Uses

Acaricide.

Safety Profile

Moderately toxic by ingestion andintraperitoneal routes. A pesticide. When heated todecomposition it emits toxic fumes of Cl-.

Upstream product

• 141-78-6 ethyl acetate 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 917-64-6 methyl magnesium iodide 
• 90-98-2 4,4'-Dichlorobenzophenone 
• 75-16-1 methylmagnesium bromide 
• 106-39-8 bromochlorobenzene 
• 75-36-5 acetyl chloride 
• 99-91-2 para-chloroacetophenone 
• 2642-81-1 1,1-bis(p-chlorophenyl)ethene 
• 108-24-7 acetic anhydride 
• 72-55-9 1,1-bis(4-chlorophenyl)-2,2-dichloroethylene 

Downstream Products

• 2642-81-1 1,1-bis(p-chlorophenyl)ethene 
• 3567-18-8 4-chloro-α-(4-chlorophenyl)-α-dichloromethylbenzenemethanol 
• 23610-15-3 1,1'-dibromo-4,4'-dichlorophenylethylene 
• 460742-75-0 4-nitro-benzoic acid 1,1-bis-(4-chloro-phenyl)-ethyl ester 
• 133216-80-5 ethyl 5,5-bis(4-chlorophenyl)-2-methyl-4,5-dihydrofuran-3-carboxylate 
• 1184002-62-7 1-amino-1,1-bis(4-chlorophenyl)ethane 
• 89500-36-7 4-chloro-N-(1-(4-chlorophenyl)ethyl)aniline 

Relevant articles and documents

Base-promoted addition of DMA with 1,1-diarylethylenes: Application to a total synthesis of (-)-sacidumlignan B

A base-promoted addition of DMA (N,N-dimethylacetamide) to 1,1-diarylethylenes has been developed, and it provides a new strategy for the synthesis of N,N-dimethyl-4,4-diarylbutanamides from 1,1-diarylethylenes at room temperature. This method allows us to achieve the goal of synthesizing (-)-sacidumlignan B, and provides simple operation and broad substrate scope by avoiding the use of transition metal catalysts.

Electrophilic borylation of terminal alkenes with BBr3/2,6-disubstituted pyridines

A variety of terminal alkenes, as well as heteroaromatic compounds, are borylated by the combined use of BBr3/2,6-dichloropyridine (B3) or BBr3/2,6-lutidine (B5). α,α-Diarylalkenes prefer the former reagent combination, while other alkenes prefer the latter. Mechanistic considerations strongly suggest that the former and latter reactions proceed through electrophilic substitution reactions with BBr3 and [BBr2·B5]+BBr4-, respectively.

Scandium(III) Trifluoromethanesulfonate Catalyzed Selective Reactions of Donor–Acceptor Cyclopropanes with 1,1-Diphenylethanols: An Approach to Polysubstituted Olefins

An unexpected synthetic approach to polysubstituted olefins through the scandium(III) trifluoromethanesulfonate catalyzed ring-opening reaction of donor–acceptor cyclopropanes with 1,1-diphenylethanols was developed. The reactions, which are experimentally easy to handle, feature tolerance of various functional groups and mild reaction conditions. On the basis of experimental evidence, a plausible mechanism was also proposed.