813459-59-5

Basic information

• Product Name: tert-butyl (1S,2R)-2-hydroxy-1,2-diphenylethylcarbamate
• Synonyms: tert-butyl (1S,2R)-2-hydroxy-1,2-diphenylethylcarbamate
• CAS NO: 813459-59-5
• Molecular Weight: 313.397
• Mol File: 813459-59-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: tert-butyl (1S,2R)-2-hydroxy-1,2-diphenylethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (1S,2R)-2-hydroxy-1,2-diphenylethylcarbamate(813459-59-5)
• EPA Substance Registry System: tert-butyl (1S,2R)-2-hydroxy-1,2-diphenylethylcarbamate(813459-59-5)

Safety Data

• Hazardous Substances Data: 813459-59-5(Hazardous Substances Data)

Upstream product

• 34619-03-9 tert-butyldicarbonate 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 451-40-1 phenyl benzyl ketone 
• 1484-50-0 desyl bromide 
• 32493-66-6 2-(2-oxo-1,2-diphenylethyl)isoindoline-1,3-dione 
• 885-75-6 2-amino-1,2-diphenyl-ethanone; hydrochloride 

Downstream Products

• 144738-22-7 (1R,2S)-2-tert-butoxycarbonylamino-1-methoxy-1,2-diphenylethane 
• 142465-03-0 ((1S,2R)-2-Methoxy-1,2-diphenyl-ethyl)-methyl-carbamic acid tert-butyl ester 
• 813459-65-3 (2S,4S,5R)-2-Oxo-4,5-diphenyl-2λ⁴-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester 
• 117857-85-9 (1S,2R)-2-methoxy-1,2-diphenylethylamine 
• 144738-23-8 (1R,2S)-2-isopropylamino-1-methoxy-1,2-diphenylethane 
• 23204-70-8 (4S,5R)-4,5-diphenyl-1,3-oxazolidin-2-one 
• 1091606-63-1 (4S,5R)-4,5-diphenyl-1,2,3-oxathiazolidine-3-carboxylic acid 1,1-dimethylethyl ester 2,2-dioxide 
• 1206227-48-6 tert-butyl (1S,2S)-2-(diphenylphosphino)-1,2-diphenylethylcarbamate 
• 1091606-67-5 (1S,2S)-2-(diphenylphosphino)-1,2-diphenylethanamine 

Relevant articles and documents

Asymmetric Transfer Hydrogenation: Dynamic Kinetic Resolution of α-Amino Ketones

A series of α-amino ketones were reduced using asymmetric transfer hydrogenation (ATH) through a dynamic kinetic resolution (DKR). The protecting group was matched to the reducing agent, and following optimization, a series of substrates were investigated, giving products in high diastereoselectivity, over 99% ee in several cases and full conversion. The methodology was applied to the enantioselective synthesis of an MDM2-p53 inhibitor precursor.

Dynamic kinetic resolution in the stereoselective synthesis of 4,5-diaryl cyclic sulfamidates by using chiral rhodium-catalyzed asymmetric transfer hydrogenation

The dynamic kinetic resolution of 4,5-diaryl cyclic sulfamidate imines was achieved via asymmetric transfer hydrogenation using a HCO2H/Et 3N mixture as the hydrogen source and chiral Rh catalysts (R,R)- or (S,S)-RhCl(TsDPEN)Cp* affo

METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS

The present application is directed to i) a two-step method for synthesizing phosphme-ammophosphme (P,N,P) ligands, ii) the use of such ligands in the preparation of metal complexes as hydrogenation catalysts, and iii) ammophosphme (P,N) and phosphme-ammo