83004-10-8

Basic information

• Product Name: 2-BROMO-6-(BROMOMETHYL)PYRIDINE
• Synonyms: PYRIDINE, 2-BROMO-6-(BROMOMETHYL)-;2-BROMO-6-(BROMOMETHYL)PYRIDINE;6-Bromo-2-bromomethylpyridine
• CAS NO: 83004-10-8
• Molecular Formula: C₆H₅Br₂N
• Molecular Weight: 250.92
• Product Categories: Heterocycle-Pyridine series
• Mol File: 83004-10-8.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 275℃
• Flash Point: 120℃
• Appearance: /
• Density: 1.955
• Vapor Pressure: 0.009mmHg at 25°C
• Refractive Index: 1.613
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.00±0.12(Predicted)
• CAS DataBase Reference: 2-BROMO-6-(BROMOMETHYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-6-(BROMOMETHYL)PYRIDINE(83004-10-8)
• EPA Substance Registry System: 2-BROMO-6-(BROMOMETHYL)PYRIDINE(83004-10-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 83004-10-8(Hazardous Substances Data)

Usage

General Description

2-Bromo-6-(bromomethyl)pyridine is a compound that contains two bromine atoms attached to a pyridine ring, with one of the bromine atoms being attached to a methyl group. This chemical is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is a versatile building block for creating complex organic molecules, particularly those with biological activity. The presence of bromine atoms on the pyridine ring can impart specific chemical properties to the compound, making it suitable for a range of applications in the pharmaceutical and agricultural industries. However, it is important to handle this chemical with care due to its potential hazards and toxicity.

InChI:InChI=1/C6H5Br2N/c7-4-5-2-1-3-6(8)9-5/h1-3H,4H2

Upstream product

• 5315-25-3 2-bromo-6-methylpyridine 
• 33674-96-3 2-bromo-6-(hydroxymethyl)pyridine 
• 1824-81-3 2-Amino-6-methylpyridine 

Downstream Products

• 882426-55-3 dibenzyl-[2-(6-bromo-pyridin-2-ylmethoxy)-1,1-bis-(6-bromo-pyridin-2-ylmethoxymethyl)-ethyl]-amine 
• 958880-85-8 (6-bromo-pyridin-2-ylmethyl)-cyclohexylmethyl-(2-trifluoromethyl-benzyl)-amine 
• 882426-56-4 C₅₁H₆₂N₄O₉ 
• 112575-11-8 2-(6-bromopyridin-2-yl)acetonitrile 
• 1187833-88-0 N-[(6-bromopyridin-2-yl)methoxy]-1-(1-methyl-1H-tetrazol-5-yl)-1-phenylmethanimine 
• 1206455-34-6 C₁₈H₁₄Br₂N₄O₄S 
• 1429913-28-9 benzyl {6-[(2-hydroxy-2-methylpropoxy)methyl]pyridin-2-yl}carbamate 
• 1446190-13-1 (2Z)-{[(6-bromopyridin-2-yl)methoxy]imino}(phenyl)acetonitrile 
• 1446190-07-3 3-[(Z)-{[(6-bromopyridin-2-yl)methoxy]imino}(phenyl)methyl]-2-methyl-1,2,4-oxadiazol-5(2H)-one 
• 1446190-14-2 (2Z)-2-{[(6-bromopyridin-2-yl)methoxy]imino}-N-hydroxy-N-methyl-2-phenylethanimidamide 
• 1184932-12-4 1-(3-chloro-2-fluorobenzoyl)-4-((6-(1H-pyrazol-3-ylamino)pyridin-2-yl)methyl)piperidine-4-carboxamide 
• 1184932-61-3 4-((6-(1H-pyrazol-3-ylamino)pyridin-2-yl)methyl)-1-(3-chloro-2-fluorobenzoyl)piperidine-4-carboxylic acid 
• 1184932-10-2 ethyl 1-(3-chloro-2-fluorobenzoyl)-4-((6-(1H-pyrazol-3-ylamino)pyridin-2-yl)methyl)piperidine-4-carboxylate 
• 1184932-74-8 5-(4-((6-((1-tert-butyl-lH-pyrazol-5-yl)amino)pyridin-2-yl)methyl)-1-(phenylsulfonyl)piperidin-4-yl)-1,3,4-oxadiazol-2(3H)-one 

Relevant articles and documents

Ruthenium complexes bearing unsymmetric CNC' pincer ligands: Molecular structures and electronic properties

Homoleptic ruthenium complexes [Ru(Ln)2]2+ bearing unsymmetric pyridine-based bis N-heterocyclic carbene (NHC) pincer ligands are synthesized and structurally characterized. These complexes feature the coexistence of a five-membered and a six-membered ruthenacycle within the same ligand framework, allowing an ideally octahedral CNHC-Ru-N Py bite angle close to 90°. In the solid state, impressive 3MLCT lifetimes of microsecond regime were detected in all of the complexes, of which [Ru(L4)2]2+, featuring four benzimidazol-2-ylidene donors, exhibited the longest values. Electronic properties of all of the ruthenium complexes are investigated by cyclic voltammetry and spectroscopic techniques. Density functional theory results were used to support the experimental observations.

Ruthenium complexes bearing N-heterocyclic carbene based CNC and CN^CH2C’ pincer ligands: Photophysics, electrochemistry, and solar energy conversion

A combination of N-heterocyclic carbene (NHC) based CNC, or CN^CH2C′ pincer ligands and carboxy-phenyl terpyridine donors is used to prepare ruthenium complexes. The unsymmetrical coordination of CN^CH2C′ pincer

TRIAZOLOPYRIMIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS

The present invention relates to compounds of general formula I, wherein the groups R1 and R2 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.

FUSED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF

The present invention relates to fused heterocyclic derivatives, processes for their preparation and their use in medicine. Specifically, the present invention relates to a novel derivative represented by the formula (I′), or its pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the derivative or its pharmaceutically acceptable salt thereof, and the method for preparing the derivative and its pharmaceutically acceptable salt thereof. The present invention also relates to the use of the derivative and its pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the derivative and its pharmaceutically acceptable salt thereof in the preparation of medicines, in particularly as IDO inhibitor medicines, for treating and/or preventing cancers. Wherein each substituent of the formula (I′) is the same as defined in the specification.