83191-20-2

Basic information

• Product Name: 2,2,2-trichloro-1-[(phenylsulfonyl)amino]ethyl acetate
• CAS NO: 83191-20-2
• Molecular Formula: C₁₀H₁₀Cl₃NO₄S
• Molecular Weight: 346.6147
• Mol File: 83191-20-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 469.6°C at 760 mmHg
• Flash Point: 237.8°C
• Density: 1.522g/cm³
• Vapor Pressure: 5.45E-09mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 2,2,2-trichloro-1-[(phenylsulfonyl)amino]ethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trichloro-1-[(phenylsulfonyl)amino]ethyl acetate(83191-20-2)
• EPA Substance Registry System: 2,2,2-trichloro-1-[(phenylsulfonyl)amino]ethyl acetate(83191-20-2)

Safety Data

• Hazardous Substances Data: 83191-20-2(Hazardous Substances Data)

Upstream product

• 473-29-0 N,N-Dichlorobenzenesulfonamide 
• 36597-97-4 β,β-dichlorovinyl acetate 
• 55596-11-7 N-(2,2,2-trichloroethylidene)benzenesulfonamide 
• 64-19-7 acetic acid 
• 83191-25-7 N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide 
• 75457-08-8 N-(2,2,2-trichloro-1-hydroxyethyl)benzenesulfonamide 
• 64-17-5 ethanol 
• 129633-30-3 N-(2,2,2-Trichloro-1-methoxy-ethyl)-benzenesulfonamide 
• 83790-88-9 N-chloro-N-(2,2,2-trichloro-1-acetoxyethyl)benzenesulfonamide 

Downstream Products

• 75457-08-8 N-(2,2,2-trichloro-1-hydroxyethyl)benzenesulfonamide 
• 83191-25-7 N-(2,2,2-trichloro-1-ethoxyethyl)benzenesulfonamide 

Relevant articles and documents

Hydrolysis of N-(2,2,2-trichloroethyl)arenesulfonamides

The direction of alkaline hydrolysis of N-(2,2,2-trichloro-1-R-ethyl)arenesulfonamides depends on the R substituent in the α-position with respect to the nitrogen atom. Substituents R having an n-donor heteroatom X promote cleavage of the C-N and C-X bonds to release the corresponding sulfonamide. Alkaline hydrolysis of N-(1-aryl-2,2,2-trichloroethyl)arenesulfonamides occurs chemoselectively at the trichloromethyl group. This reaction can be regarded as a preparative route to N-arylsulfonyl-α-arylglycines.

REACTIONS OF β,β-DICHLOROVINYL ACETATE WITH N,N-DICHLOROARENESULFAMIDINES

N-Chloro-N-(2,2,2-trichloro-1-acetoxyethyl)arenesulfonamides are formed with high yields in the reaction of β,β-dichlorovinyl acetate with N,N-dichloroarenesulfamidines.They readily exchange the acetoxy group for alkoxy, alkylthio, and alkylamino groups (