83610-02-0

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-2,6-diphenyl-4-thioxo-, ethyl ester
• CAS NO: 83610-02-0
• Molecular Formula: C19H16N2O2S
• Molecular Weight: 336.414
• Mol File: 83610-02-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-2,6-diphenyl-4-thioxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-2,6-diphenyl-4-thioxo-, ethyl ester(83610-02-0)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-2,6-diphenyl-4-thioxo-, ethyl ester(83610-02-0)

Safety Data

• Hazardous Substances Data: 83610-02-0(Hazardous Substances Data)

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 64502-69-8 3,5-diphenyl-1,2,4-dithiazol-1-ium perchlorate 
• 101185-06-2 2-Cyan-3-phenyl-3-thiobenzoylamido-acrylsaeureethylester 
• 101185-06-2 (E)-2-Cyano-3-phenyl-3-thiobenzoylamino-acrylic acid ethyl ester 

Relevant articles and documents

Synthesis of Pyrimidine Derivatives Having Oxo, Thioxo or Amino Functions at Position 4 from 1,2,4-Dithiazolium Salts

The (thioaroylamido)acrylonitriles 2, obtained by reaction of 1,2,4-dithiazolium salts 1 with ethyl cyanacetate, undergo ring tranformation reactions by reaction with ammonium acetate, primary and secondary amines and form the pyrimidines 7-9.A possible mechanism for these reactions is discussed.

The Reaction of 3,5-Diphenyl-1,2,4-dithiazol-1-ium Perchlorate with Active Methylene Compounds

The reaction of 3,5-diphenyl-1,2,4-dithiazol-1-ium perchlorate with several kinds of active methylenes gives a number of heterocycles, such as 4-hydroxy and 4-mercaptopyrimidine, pyrimidinone, and thiazole derivatives.On treatment with hydroxylamine-O-sulfonic acid, the 4-mercaptopyrimidines lead to the aminothio compounds or the isothiazolopyrimidine.