83784-20-7

Basic information

• Product Name: Hydrocortisone hemisuccinate hydrate
• Synonyms: CORTISOL HEMISUCCINATE MONOHYDRATE;HYDROCORTISONE HEMISUCCINATE, MONOHYDRATE;HYDROCORTISONEHEMISUCCINATE,MONOHYDRATE,USP;Hydrocortisone hemisuccinate hydrate;(11b-)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxypregn-4-ene-3,20-dione monohydrate;4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]-4-oxo-butanoic acid hydrate;4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid hydrate;4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-keto-ethoxy]-4-keto-butyric acid hydrate
• CAS NO: 83784-20-7
• Molecular Formula: C25H36O9
• Molecular Weight: 480.55
• Product Categories: Steroids
• Mol File: 83784-20-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Acetone (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Hydrocortisone hemisuccinate hydrate(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrocortisone hemisuccinate hydrate(83784-20-7)
• EPA Substance Registry System: Hydrocortisone hemisuccinate hydrate(83784-20-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 83784-20-7(Hazardous Substances Data)

Usage

Description

Hydrocortisone hemisuccinate hydrate is a metabolite of Hydrocortisone, a steroid hormone and a glucocorticoid produced by the zona fasciculata of the adrenal gland. It is released in response to stress and low levels of blood glucocorticoids.

Uses

Used in Pharmaceutical Industry:
Hydrocortisone hemisuccinate hydrate is used as an anti-inflammatory and immunosuppressive agent for treating various conditions such as rheumatoid arthritis, lupus, and asthma. Its ability to reduce inflammation and suppress the immune system makes it a valuable treatment option for these conditions.
Used in Emergency Medicine:
Hydrocortisone hemisuccinate hydrate is used as a life-saving medication in the treatment of anaphylaxis, a severe allergic reaction that can cause airway constriction and shock. Its rapid onset of action and ability to counteract the effects of the immune system make it an essential component in emergency medicine.
Used in Adrenal Insufficiency Treatment:
Hydrocortisone hemisuccinate hydrate is used as a replacement therapy for patients with adrenal insufficiency, a condition where the adrenal glands do not produce enough cortisol. By providing the necessary hormone, it helps to alleviate symptoms and maintain normal bodily functions.
Used in Skin Conditions:
Hydrocortisone hemisuccinate hydrate is used as a topical treatment for various skin conditions, such as eczema, dermatitis, and psoriasis. Its anti-inflammatory properties help to reduce redness, itching, and swelling associated with these conditions, providing relief and promoting healing.