841290-81-1 Usage
Description
R406 is a potent Syk inhibitor that modulates Dectin-1-mediated signaling in mammalian cells, making it a promising candidate for various therapeutic applications.
Uses
Used in Antifungal Applications:
R406 is used as an antifungal agent, targeting Dectin-1-mediated signaling pathways to inhibit fungal growth and prevent infections.
Used in Anti-leukemia Applications:
R406 is used as a potential anti-leukemia agent, modulating the sphingosine-1 phosphate receptor 1 (S1PR1) to affect leukemic cell behavior and potentially treat leukemia.
Used in Immunology Research:
R406 is used as a research tool in immunology, helping scientists understand the role of Syk inhibitors and Dectin-1-mediated signaling in immune responses and the development of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 841290-81-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,1,2,9 and 0 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 841290-81:
(8*8)+(7*4)+(6*1)+(5*2)+(4*9)+(3*0)+(2*8)+(1*1)=161
161 % 10 = 1
So 841290-81-1 is a valid CAS Registry Number.
841290-81-1Relevant articles and documents
2,4-PYRIMIDINEDIAMINE COMPOUNDS FOR USE IN THE TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES
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Page/Page column 70; 101, (2010/02/10)
The present invention provides methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds, as well as methods of treating, preventing or ameliorating symptoms associated with such diseases. Specific examples of autoimmune diseases that can be treated or prevented with the compounds include rheumatoid arthritis and/or its associated symptoms, systemic lups erythematosis and/or its associated symptoms and multiple sclerosis and/or its associated symptoms.