848952-83-0

Basic information

• Product Name: 5-Chloropyrazine-2-carboxylic acid hydrazide
• Synonyms: 5-Chloropyrazine-2-carboxylic acid hydrazide;5-chloropyrazine-2-carbohydrazide;5-chloropyrazine-2-carboxylic acid hydyazide
• CAS NO: 848952-83-0
• Molecular Formula: C₅H₅ClN₄O
• Molecular Weight: 172.574
• EINECS: 1312995-182-4
• Mol File: 848952-83-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.496g/cm³
• Refractive Index: 1.607
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.51±0.10(Predicted)
• CAS DataBase Reference: 5-Chloropyrazine-2-carboxylic acid hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloropyrazine-2-carboxylic acid hydrazide(848952-83-0)
• EPA Substance Registry System: 5-Chloropyrazine-2-carboxylic acid hydrazide(848952-83-0)

Safety Data

• Hazardous Substances Data: 848952-83-0(Hazardous Substances Data)

Usage

General Description

5-Chloropyrazine-2-carboxylic acid hydrazide is a chemical compound with the molecular formula C5H5ClN4O. It is a hydrazide derivative of pyrazine carboxylic acid, containing a chloro substituent at position 5 of the pyrazine ring. 5-Chloropyrazine-2-carboxylic acid hydrazide has potential use in pharmaceutical and agricultural applications due to its properties as a building block for various chemical syntheses and as a potential precursor for the synthesis of bioactive compounds. It may also have potential as a pesticide or herbicide due to its structural similarity to other known agricultural chemicals. Overall, 5-Chloropyrazine-2-carboxylic acid hydrazide is a versatile chemical with potential uses in various industries and applications.

InChI:InChI=1/C5H5ClN4O/c6-4-2-8-3(1-9-4)5(11)10-7/h1-2H,7H2,(H,10,11)

Upstream product

• 54013-04-6 ethyl 5-chloro-2-pyrazinecarboxylate 
• 36070-80-1 5-chloropyrazinoic acid 
• 1254073-53-4 1,1-dimethylethyl 2-[(5-chloro-2-pyrazinyl)carbonyl]hydrazinecarboxylate 
• 33332-25-1 methyl 5-chloropyrazine-2-carboxylate 

Downstream Products

• 848952-92-1 2-chloro-5-(5-methyl-[1,3,4]oxadiazol-2-yl)-pyrazine 

Relevant articles and documents

Synthesis and anticancer activity of new hydrazide-hydrazones and their Pd(II) complexes

Background: Hydrazones, one of the important classes of organic molecules, are pharmaceutical agents comprising –CO-NH-N=CH- group in the structure therefore and exhibiting significant biological activity. Methods: 5-Chloro-N’-[(substituted)methylidene] p

5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein A is hydrogen, C1-4alkyl, C3-6cycloalkyl, C1-3alkoxy, C1-3alkoxy C1-4alkyl, C1-2fluoroalkyl, halogen, NR6 R7, optionally substituted heteroaryl (Het), or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis, osteoarthritis or neurodegenerative disorders.

SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS

The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a var