85719-72-8

Basic information

• Product Name: Pyridine, 3-[[(trimethylsilyl)oxy]methyl]- (9CI)
• Synonyms: Pyridine, 3-[[(trimethylsilyl)oxy]methyl]- (9CI)
• CAS NO: 85719-72-8
• Molecular Formula: C₉H₁₅NOSi
• Molecular Weight: 181.307
• Product Categories: SILYL
• Mol File: 85719-72-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyridine, 3-[[(trimethylsilyl)oxy]methyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 3-[[(trimethylsilyl)oxy]methyl]- (9CI)(85719-72-8)
• EPA Substance Registry System: Pyridine, 3-[[(trimethylsilyl)oxy]methyl]- (9CI)(85719-72-8)

Safety Data

• Hazardous Substances Data: 85719-72-8(Hazardous Substances Data)

Upstream product

• 85719-71-7 methylbis(1-methylethoxy)(3-pyridylmethyl)silane 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 100-55-0 3-hydroxymethylpyridin 
• 626-55-1 3-Bromopyridine 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 65362-92-7 (3,5-di-tert-butyl-4-hydroxyphenyl)methyl-(3-pydidyl)methyl ether 
• 100-55-0 3-hydroxymethylpyridin 

Relevant articles and documents

KF/clinoptilolite NPs: An efficient and heterogeneous catalyst for chemoselective silylation of alcohols and phenols

Potassium fluoride incorporated on clinoptilolite nanoparticles (KF/CP NPs) by ion exchanging is found to be an effective and inexpensive heterogeneous nanocatalyst for chemoselective silylation of alcohols and phenols with 1,1,1,3,3,3-hexamethyldisilazane (HMDS) at room temperature. Nano-powder of clinoptilolite (CP) was prepared using a planetary ball mill mechanically method and characterized by dynamic light scattering (DLS), X-ray powder diffraction (XRD) and scanning electron microscope (SEM) analyses. Almost all of products were obtained in high yields as well as short reaction times and the catalyst was also reused eight times without loss of its catalytic activity.

Highly efficient and chemoselective trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) catalyzed by reusable electron-deficient [TiIV(salophen)(OTf)2]

In the present work, highly efficient trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) catalyzed by high-valent [Ti IV(salophen)(OTf)2] is reported. Under these conditions, primary, secondary and tertiary alcohols as well as phenols were silylated in short reaction times and high yields. It is noteworthy that this method can be used for chemoselective silylation of primary alcohols in the presence of secondary and tertiary alcohols and phenols. The catalyst was reused several times without loss of its catalytic activity.

Polyvinylpolypyrrolidoniume tribromide as new and metal-free catalyst for the formylation and trimethylsilylation of hydroxyl group

Trimethylsilylation of alcohols was achieved using 1,1,1,3,3,3- hexamethyldisilazane (HMDS) as silylating agent, in the presence of polyvinylpolypyrrolidoniume tribromide in acetonitrile at room temperature. Also a variety of alcohols were converted into alkyl formates by ethyl formate and a catalytic amount of polyvinylpolypyrrolidoniume tribromide under solvent free conditions at room temperature.