861103-21-1

Basic information

• Product Name: Benzoic acid, 4-[[(2,2-dimethoxyethyl)amino]carbonyl]-, methyl ester
• CAS NO: 861103-21-1
• Molecular Formula: C13H17NO5
• Molecular Weight: 267.282
• Mol File: 861103-21-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[[(2,2-dimethoxyethyl)amino]carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[[(2,2-dimethoxyethyl)amino]carbonyl]-, methyl ester(861103-21-1)
• EPA Substance Registry System: Benzoic acid, 4-[[(2,2-dimethoxyethyl)amino]carbonyl]-, methyl ester(861103-21-1)

Safety Data

• Hazardous Substances Data: 861103-21-1(Hazardous Substances Data)

Upstream product

• 1679-64-7 Monomethyl terephthalate 
• 22483-09-6 2,2-dimethoxyethylamine 
• 7377-26-6 4-Methoxycarbonylbenzoyl chloride 

Downstream Products

• 66-27-3 Methyl methanesulfonate 
• 421553-40-4 methyl 4-(oxazol-2-yl)benzoate 

Relevant articles and documents

Ring size changes in the development of class I HDAC inhibitors

Five pathways involving different ring structures led to generation of fourteen thienylbenzamides (7–20) which display the structure-activity relationships of class I HDAC inhibitors. All the synthesised compounds inhibit HDAC1 and HDAC2 selectively over other isoforms and many inhibit DLD1 and HCT116 cells more effectively than a parent compound. Compounds 8 and 16 inhibit HCT116 cells by activation of the apoptosis pathway.