86364-03-6

Basic information

• Product Name: 3-Chlorophenyl trifluoromethanesulphonate
• Synonyms: 3-Chlorophenyl trifluoromethanesulphonate
• CAS NO: 86364-03-6
• Molecular Formula: C₇H₄ClF₃O₃S
• Molecular Weight: 260.6180696
• Mol File: 86364-03-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 272.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.600±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3-Chlorophenyl trifluoromethanesulphonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chlorophenyl trifluoromethanesulphonate(86364-03-6)
• EPA Substance Registry System: 3-Chlorophenyl trifluoromethanesulphonate(86364-03-6)

Safety Data

• Hazardous Substances Data: 86364-03-6(Hazardous Substances Data)

Upstream product

• 108-43-0 3-monochlorophenol 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 1493-13-6 trifluorormethanesulfonic acid 
• 456-39-3 3-chlorobenzenediazonium tetrafluoroborate 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 131543-57-2 (S)-2-(3-chlorophenyl)-2,3-dihydrofuran 
• 131543-57-2 (R)-2-(3-chlorophenyl)-2,3-dihydrofuran 
• 131516-12-6 (R)-2-(3-chlorophenyl)-2,5-dihydrofuran 
• 131516-12-6 (S)-2-(3-chlorophenyl)-2,5-dihydrofuran 
• 1043912-25-9 3-chloro-2-trifluoromethanesulphonylphenol 
• 1196151-10-6 3-(2-phenylethynyl)phenyl trifluoromethanesulfonate 
• 23415-68-1 Diphenyl-(3-chlorphenyl)-phosphinoxid 
• 111164-13-7 (3-chloro-phenyl)-phenyl-phosphinic acid ethyl ester 
• 23415-71-6 3-Chlorphenylphosphonsaeurediethylester 
• 23415-66-9 (3-chlorophenyl)diphenylphosphine 
• 852204-45-6 dimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)phosphonate 
• 36383-13-8 1-(sec-butyl)-3-chlorobenzene 
• 2051-61-8 m-chlorobiphenyl 
• 135334-14-4 2-(3-chlorophenyl)-2,2-difluoroacetic acid ethyl ester 

Relevant articles and documents

Inverting Conventional Chemoselectivity in the Sonogashira Coupling Reaction of Polyhalogenated Aryl Triflates with TMS-Arylalkynes

A newly developed phosphine ligand with a C2-cyclohexyl group on the indole ring was successfully applied in a chemoselective Sonogashira coupling reaction with excellent chemoselectivity, affording an inversion of the conventional chemoselectivity order of C–Br > C–Cl > C–OTf. This study also provided an efficient approach to the synthesis of polycyclic aromatic hydrocarbons (PAHs) and the natural product analogue trimethyl-selaginellin L by merging of chemoselective Sonogashira and Suzuki–Miyaura coupling reactions.

Modular Functionalization of Arenes in a Triply Selective Sequence: Rapid C(sp2) and C(sp3) Coupling of C?Br, C?OTf, and C?Cl Bonds Enabled by a Single Palladium(I) Dimer

Full control over multiple competing coupling sites would enable straightforward access to densely functionalized compound libraries. Historically, the site selection in Pd0-catalyzed functionalizations of poly(pseudo)halogenated arenes has been unpredictable, being dependent on the employed catalyst, the reaction conditions, and the substrate itself. Building on our previous report of C?Br-selective functionalization in the presence of C?OTf and C?Cl bonds, we herein complete the sequence and demonstrate the first general arylations and alkylations of C?OTf bonds (in I dimer. This allowed the realization of the first general and triply selective sequential C?C coupling (in 2D and 3D space) of C?Br followed by C?OTf and then C?Cl bonds.

Low-Temperature Ag/Pd-catalyzed decarboxylative cross-coupling of aryl trflates with aromatic carboxylate salts

Chemical Equation Presented At 50°C lower than the best known copper catalysts, a catalytic silver(I)/ palladium(II) system allows the decarboxylative cross-coupling of arenecarboxylates with aryl triflates at temper-atures as low as 120°C. Remarkably, polychlorinated and many heterocyclic arenecarboxylates are converted for the first time in high yields. FG = functional group.