869886-90-8

Basic information

• Product Name: 4-(5-chloro-2-(isopropylaMino)pyridin-4-yl)-1H-pyrrole-2-carboxylic acid
• Synonyms: 4-(5-chloro-2-(isopropylaMino)pyridin-4-yl)-1H-pyrrole-2-carboxylic acid
• CAS NO: 869886-90-8
• Molecular Formula: C₁₃H₁₄ClN₃O₂
• Molecular Weight: 279.72216
• Mol File: 869886-90-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(5-chloro-2-(isopropylaMino)pyridin-4-yl)-1H-pyrrole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-chloro-2-(isopropylaMino)pyridin-4-yl)-1H-pyrrole-2-carboxylic acid(869886-90-8)
• EPA Substance Registry System: 4-(5-chloro-2-(isopropylaMino)pyridin-4-yl)-1H-pyrrole-2-carboxylic acid(869886-90-8)

Safety Data

• Hazardous Substances Data: 869886-90-8(Hazardous Substances Data)

Upstream product

• 405230-81-1 2,5-dichloro-4-nitropyridine-1-oxide 
• 40740-41-8 methyl 4-iodo-1H-pyrrole-2-carboxylic acid ester 
• 53976-62-8 2,5-dichloro-1-oxido-pyridin-1-ium 
• 72652-33-6 4-iodo-2-(trichloroacetyl)pyrrole 
• 869886-92-0 4-(5-chloro-2-isopropylamino-pyridin-4-yl)-1-(2,4,6-trimethyl-benzenesulfonyl)-1H-pyrrole-2-carboxylic acid methyl ester N-oxide 
• 869886-86-2 methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)-1-p-toluenesulfonyl-1H-pyrrole-2-carboxylate 
• 869886-84-0 C₅H₂BrCl₂NO 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 
• 16110-09-1 2,5 dichloropyridine 
• 869886-85-1 4-iodo-1-(toluene-4-sulfonyl)-1H-pyrrole-2-carboxylic acid methyl ester 
• 869886-87-3 5-chloro-4-iodo-N-isopropylpyridin-2-amine 
• 659731-48-3 5-chloro-2-fluoro-4-iodopyridine 
• 869886-89-5 4-(5-chloro-2-isopropylaminopyridin-4-yl)-1-(2,4,6-trimethylbenzenesulfonyl)-1H-pyrrole-2-carboxylic acid methyl ester 
• 869886-88-4 4-(5-chloro-2-isopropylaminopyridin-4-yl)-1-(toluene-4-sulfonyl)-1H-pyrrole-2-carboxylic acid methyl ester 

Downstream Products

• 1956366-10-1 4-(5-chloro-2-isopropylaminopyridin-4-yl)-1H-pyrrole-2-carboxylicacid[1-(3-chlorophenyl)-2-hydroxyethyl]amide hydrochloride 
• 869886-67-9 4-[5-chloro-2-[(1-methylethyl)amino]-4-pyridinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide 

Relevant articles and documents

ERK INHIBITOR AND USE THEREOF

Disclosed are a compound (as shown in formula I) as an extracellular signal-regulated kinase (ERK) inhibitor, a pharmaceutical composition thereof, a preparation method therefor, and use thereof in treating ERK-mediated diseases. Said compound plays a role by regulating a plurality of processes such as cell proliferation, apoptosis, migration and angiogenesis.

CRYSTALLINE C21H22C12N4O2 MALONATE

The present invention provides a malonate salt of a compound of formula (I), which is a crystalline salt. Also provided are pharmaceutical compositions that include the provided malonate salt and methods of using the provided crystalline forms and pharmaceutical compositions for the treatment of cancer.