87148-44-5Relevant articles and documents
REACTIVITY OF CHLOROSUBSTITUTED α-EPOXIDES AND SYNTHESES UNDER THESE COMPOUNDS
Voronina, T. A.,Fomina, N. V.,Suminov, S. I.
, p. 1059 - 1063 (2007/10/02)
The reactivity of chloroepoxyethanes in reactions with nucleophiles and electrophiles increases sharply with the accumulation of chlorine atoms on the epoxide ring.The reaction rate correlates with the nucleophile strength.Reactions with strong nucleophiles proceed through epoxide isomerization and lead to chloroacetic acid derivatives.Addition to the epoxide ring is found only for several weak nucleophiles.