876030-88-5

Basic information

• Product Name: Benzamide, 5-bromo-2-[(3-chloro-1-oxopropyl)amino]-
• CAS NO: 876030-88-5
• Molecular Formula: C10H10BrClN2O2
• Molecular Weight: 305.559
• Mol File: 876030-88-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, 5-bromo-2-[(3-chloro-1-oxopropyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 5-bromo-2-[(3-chloro-1-oxopropyl)amino]-(876030-88-5)
• EPA Substance Registry System: Benzamide, 5-bromo-2-[(3-chloro-1-oxopropyl)amino]-(876030-88-5)

Safety Data

• Hazardous Substances Data: 876030-88-5(Hazardous Substances Data)

Upstream product

• 19434-65-2 3-chloropropanaldehyde 
• 16313-66-9 5-bromoanthranilamide 

Relevant articles and documents

Isoxazolidine conjugates of N3-substituted 6-bromoquinazolinones—synthesis, anti-varizella-zoster virus, and Anti-cytomegalovirus activity

1,3-Dipolar cycloaddition of N-methyl C-(diethoxyphosphoryl) nitrone to N3-substituted 6-bromo-2-vinyl-3H-quinazolin-4-ones gave (3-diethoxyphosphoryl) isoxazolidines substituted at C5 with quinazolinones modified at N3. All isoxazolidine cycloadducts were screened for antiviral activity against a broad spectrum of DNA and RNA viruses. Several isoxazolidines inhibited the replication of both thymidine kinase wild-type and deficient (TK+ and TK?) varicella-zoster virus strains at EC50 in the 5.4–13.6 μM range, as well as human cytomegalovirus (EC50 = 8.9–12.5 μM). Isoxazolidines trans-11b, trans-11c, trans-11e, trans-11f/cis-11f, trans-11g, trans-11h, and trans-11i/cis-11i exhibited moderate cytostatic activity towards the human lymphocyte cell line CEM (IC50 = 9.6–17 μM).