894351-87-2 Usage
Type of compound
Potent 5-HT3 receptor antagonist
Potential use
Treatment of various neurological disorders, including cognitive impairments and psychiatric conditions (e.g. Alzheimer's disease, schizophrenia)
Mechanism of action
Selectively blocking the activity of 5-HT3 receptors, which regulate neurotransmission and synaptic plasticity in the brain
Preclinical results
Promising
Further research
Needed to understand the efficacy and safety of the compound for potential medical uses.
Check Digit Verification of cas no
The CAS Registry Mumber 894351-87-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,4,3,5 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 894351-87:
(8*8)+(7*9)+(6*4)+(5*3)+(4*5)+(3*1)+(2*8)+(1*7)=212
212 % 10 = 2
So 894351-87-2 is a valid CAS Registry Number.
894351-87-2Relevant articles and documents
A PROCESS FOR THE SYNTHESIS OF NARATRIPTAN
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Page/Page column 27; 41, (2011/04/13)
The present invention relates to a process for preparing naratriptan or a salt thereof, the process comprising: (a) reacting a compound of formula (3) with a compound of the formula HCCR wherein Z is a protecting group, Y is a leaving group and R is a trialkyl silyl group, a trialkylstannyl group or a zinc (II) halide, to obtain the compound of formula (4); (b) converting the compound of formula (4) to a compound of formula (5) wherein Z'' is hydrogen or a benzyl group; (c) converting the compound of formula (5) to naratriptan; and (d) optionally converting naratriptan to a salt thereof. The present invention also provides novel compounds (3) and (4) and processes for their preparation.
