90-76-6

Basic information

• Product Name: 2-amino-2-deoxy-D-galactopyranose
• Synonyms: 2-Amino-2-deoxy-D-galactopyranose; 7535-00-4; D-Chondrosamine; D-galactopyranose, 2-amino-2-deoxy-; Galactopyranose, 2-amino-2-deoxy-, D-; GalN
• CAS NO: 90-76-6
• Molecular Formula: C₆H₁₃NO₅
• Molecular Weight: 179.1711
• Mol File: 90-76-6.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 449.9°C at 760 mmHg
• Flash Point: 225.9°C
• Density: 1.563g/cm³
• Vapor Pressure: 5.53E-10mmHg at 25°C
• Refractive Index: 1.6
• PKA: 12.27±0.70(Predicted)
• CAS DataBase Reference: 2-amino-2-deoxy-D-galactopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-2-deoxy-D-galactopyranose(90-76-6)
• EPA Substance Registry System: 2-amino-2-deoxy-D-galactopyranose(90-76-6)

Safety Data

• Hazardous Substances Data: 90-76-6(Hazardous Substances Data)

Upstream product

• 2776-93-4 2-acetamido-1-N-(L-β-aspartyl)-2-deoxy-β-D-glucopyranosylamine 
• 29625-73-8 2-acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-1-N-(4-L-aspartoyl)-2-deoxy-β-D-glucopyranosylamine 
• 16405-05-3 2-acetamido-1-N-(1-benzyloxy-N-benzyloxycarbonyl-4-L-aspartyl)-2-deoxy-β-D-glucopyranosylamine 
• 111286-55-6 2-deoxy-2-<(4,4-dimethyl-2,6-dioxocyclohexylidenemethyl)amino>-α,β-D-glucopyranose 
• 107-18-6 allyl alcohol 
• 29886-32-6 β-D-GlcpNAc(1->4)-D-GlcNAc-ol 
• 91032-39-2 C₆₆H₅₈Cl₂N₈O₂₃ 
• 7284-16-4 p-nitrophenyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→4)-2-acetamido-2-deoxy-β-D-glucopyranoside 
• 57-48-7 D-Fructose 
• 1415305-17-7 4,6-dimethoxy-1,3,5-triazin-2-yl β-D-glucosamine hydrochloride 
• 9005-49-6 heparin 
• 9050-30-0 heparan sulfate 
• 24967-93-9 chondroitin sulfate 
• 24967-94-0 dermatan sulfate 

Downstream Products

• 6857-22-3 N-(2,4,5-trihydroxy-6-hydroxymethyl-tetrahydropyran-3-yl)butyramide 
• 24916-33-4 N-<2-Desoxy-glucosyl>-N'-phenyl-thioharnstoff 
• 79698-60-5 Imidazole-1-sulfonic acid (2R,4aR,6S,7R,8R,8aR)-7-benzyloxycarbonylamino-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 10022-13-6 1,3,4,6-tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose 
• 111286-55-6 2-deoxy-2-<(4,4-dimethyl-2,6-dioxocyclohexylidenemethyl)amino>-α,β-D-glucopyranose 
• 70866-07-8 N₁-(2-chloroethyl)-N₃-glucosamino-N₁-nitrosourea 
• 41107-82-8 2,5-anhydro-D-mannitol 
• 112578-78-6 2-acetamido-3,4,5,6-tetra-O-acetyl-2-deoxy-D-galactose diethyl dithioacetal 
• 4239-72-9 ethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-galactopyranoside 
• 134122-75-1 (4R)-5-hydroxy-4-(D-arabino-tetritol-1-yl)-1-p-tolylimidazolidine-2-thione 
• 134122-77-3 2-deoxy-2-(3-phenylureido)-D-glucopyranose 
• 30595-40-5 (4R)-5-hydroxy-1-phenyl-4-(D-arabino-tetritol-1-yl)-imidazolidine-2-thione 
• 158412-81-8 (4R,5R)-5-hydroxy-1-phenyl-4-(D-arabino-tetritol-1-yl)-imidazolidine-2-thione 
• 13032-89-8 2-benzamido-1,3,4,6-tetra-O-benzoyl-2-deoxy-α-D-galactopyranose 

Relevant articles and documents

Anti-hepatitis b virus norbisabolane sesquiterpenoids from phyllanthus acidus and the establishment of their absolute configurations using theoretical calculations

Nineteen new highly oxygenated norbisabolane sesquiterpenoids, phyllanthacidoid acid methyl ester (1), and C-T (4-21), were isolated from Phyllanthus acidus Skeels, together with two known ones, phyllanthusols A (2) and B (3), whose sugar moiety was revised as glucosamine-N-acetate, rather than the previously assigned mannosamine-N-acetate. Compounds 2 and 3 were renamed respectively as phyllanthacidoids A (2) and B (3) to avoid confusion. All of the isolates except for 1 are glycosides, whose saccharide moieties possess a pentaoxy cyclohexane (scyllo quercitol) connecting with glucosamine-N-acetate or glucosyl moieties, which are first examples in natural products. Phyllanthacidoids N-R (15-19) with 8R configurations and/or 5,8-diketal skeleton, are unprecedented structures among norbisabolane sesquiterpenoids. Phyllanthacidoids S (20) and T (21) have the unusual tricyclo [3.1.1.1] oxygen bridge skeleton formed by a diketal system, of which the relative configurations of the aliphatic chain were assigned on the basis of heteronuclear coupling constants. The absolute configurations of compounds (1-21) were established by means of calculated electronic circular dichroism (ECD) and coupling constants. Compounds 1-5, 7-9, 10, and 14 displayed potential anti-hepatitis B virus (HBV) activities, with IC50 values of 0.8-36 μM against HBV surface antigen (HBsAg) and HBV excreted antigen (HBeAg), and the results indicated that the 5-ketal group and sugar moieties had contributions to the selectivity of HBsAg and HBeAg.

CHONDROITIN COMPLEXES FOR TRANSCUTANEOUS ABSORPTION

The present invention relates to the use of chondroitin as a transdermal carrier and slow-release system for active ingredients in pharmaceutical and cosmeceutical compositions.

4,6-dimethoxy-1,3,5-triazin-2-yl-d-glycosaminides: Novel substrates for transglycosylation reaction catalyzed by exo-d-glucosaminidase from amycolatopsis orientalis

A novel sugar adduct, 4,6-dimethoxy-1,3,5-triazin-2-yl-d-glucosaminide (GlcN-DMT), has been prepared by the reaction of d-glucosamine (GlcN) and 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-morpholinium chloride (DMT-MM). The adduct was recognized by exo-d-glucosaminidase (GlcNase) from Amycolatopsis orientalis and transferred the GlcN moiety, giving rise to the corresponding glucosaminides. This chemo-enzymatic process was successfully applied to d-galactosamine (GalN). GalN-DMT prepared directly from GalN and DMT-MM behaved as an efficient glycosyl donor for transfer of the GalN moiety catalyzed by the same enzyme. The introduction of the 4,6-dimethoxy-1,3,5-triazin-2-yl leaving group to the anomeric center significantly enhanced transglycosylating ability, resulting in the efficient glycosidase-catalyzed synthesis of glycosaminides.