906-33-2 Usage
Description
Neochlorogenic acid, also known as (E)-Neochlorogenic acid, is a cinnamate ester derived from the formal condensation of the carboxy group of trans-caffeic acid with the 5-hydroxy group of quinic acid. It is a primary reference substance with assigned absolute purity, considering chromatographic purity, water, residual solvents, and inorganic impurities. Produced by PhytoLab GmbH & Co. KG, this antioxidant compound is known for its potential in treating oxidative stress and related afflictions.
Uses
Used in Pharmaceutical Industry:
Neochlorogenic acid is used as an antioxidant compound for its potential in treating oxidative stress and related afflictions. Its ability to combat oxidative stress makes it a promising candidate for various pharmaceutical applications, including the development of drugs targeting conditions associated with oxidative stress.
Used in Nutraceutical Industry:
In the nutraceutical industry, Neochlorogenic acid is used as a dietary supplement for its antioxidant properties. It can help support overall health by reducing oxidative stress and promoting a balanced internal environment.
Used in Cosmetic Industry:
Neochlorogenic acid is also used in the cosmetic industry as an ingredient in skincare products. Its antioxidant properties can help protect the skin from environmental stressors and promote a healthy, youthful appearance.
Used in Food and Beverage Industry:
In the food and beverage industry, Neochlorogenic acid is used as a natural preservative and antioxidant. It can help extend the shelf life of products and maintain their quality by neutralizing harmful free radicals and preventing oxidation.
Biochem/physiol Actions
Neochlorogenic acid has been found to have an inhibitory effect on the biosynthesis of melanin. Therefore it can be used on harvested fruits to prevent brown rot infection caused by?Monilinia laxa. It also shows impressive antioxidant, antibacterial, antiviral and antipyretic characteristics. Neochlorogenic acid has the potential to be used in the management of acute and chronic inflammatory diseases due to its anti-inflammatory activity. It may function as chemopreventive compounds due to growth inhibition seen in breast cancer cell line MDA-MB-435.
Check Digit Verification of cas no
The CAS Registry Mumber 906-33-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,0 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 906-33:
(5*9)+(4*0)+(3*6)+(2*3)+(1*3)=72
72 % 10 = 2
So 906-33-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14+,16-/m1/s1
906-33-2Relevant articles and documents
Efficient and versatile synthesis of 5-O-acylquinic acids with a direct esterification using a p-methoxybenzyl quinate as a key intermediate
Oyama, Kin-Ichi,Watanabe, Noriyuki,Yamada, Tomomi,Suzuki, Masako,Sekiguchi, Yukiko,Kondo, Tadao,Yoshida, Kumi
, p. 3120 - 3130 (2015/05/04)
An efficient and versatile synthesis of 5-O-acylquinic acids from commercially available (-)-quinic acid was accomplished. We designed p-methoxybenzyl quinate as a key intermediate, and two problems, the esterification of the sterically hindered 5-OH group for the concise divergent synthesis and the low yield of the final deprotection step, were solved. For the first problem, we improved Tanabe's method, TsCl/NMI-mediated esterification using free carboxylic acids, by the addition of i-Pr2NEt. For the second problem, we established a TFA- or BCl3/C6HMe5-catalyzed deprotection reaction for the final deprotection step. 5-O-Acylquinic acids were synthesized in seven steps with 45-60% overall yield.
Synthesis of designed acylquinic acid derivatives involved in blue color development of hydrangea and their co-pigmentation effect
Toyama-Kato, Yuki,Kondo, Tadao,Yoshida, Kumi
, p. 239 - 254 (2008/03/12)
The blue sepal color of hydrangea may be developed by an unstable stipramolecular metal-complex pigment composed of delphinidin 3-glucoside (1), 5-O-caffeoylquinic acid (2) and 5-O-p-coumaroylquinic acid (3) as co-pigments and Al3+ in aqueous s
Essential structure of co-pigment for blue sepal-color development of hydrangea
Kondo, Tadao,Toyama-Kato, Yuki,Yoshida, Kumi
, p. 6645 - 6649 (2007/10/03)
Blue sepal-color of Hydrangea macrophylla might be due to a supramolecular metal-complex pigment consisting of delphinidin 3-glucoside (1), co-pigments (5-O-caffeoylquinic acid (2), and/or 5-O-p-coumaroylquinic acid (3)) and Al 3+ in an aqueous