914912-03-1

Basic information

• Product Name: 4-chlorophenyl [[(1S)-1-(1-methylethoxycarbonyl)ethyl]amino]phosphorochloridate
• Synonyms: 4-chlorophenyl [[(1S)-1-(1-methylethoxycarbonyl)ethyl]amino]phosphorochloridate
• CAS NO: 914912-03-1
• Molecular Weight: 340.143
• Mol File: 914912-03-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-chlorophenyl [[(1S)-1-(1-methylethoxycarbonyl)ethyl]amino]phosphorochloridate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chlorophenyl [[(1S)-1-(1-methylethoxycarbonyl)ethyl]amino]phosphorochloridate(914912-03-1)
• EPA Substance Registry System: 4-chlorophenyl [[(1S)-1-(1-methylethoxycarbonyl)ethyl]amino]phosphorochloridate(914912-03-1)

Safety Data

• Hazardous Substances Data: 914912-03-1(Hazardous Substances Data)

Upstream product

• 39613-92-8 alanine isopropyl ester hydrochloride 
• 772-79-2 4-chlorophenylphosphorodichloridate 
• 39613-92-8 (R)-1-isopropoxy-1-oxopropan-2-aminium chloride 

Downstream Products

• 1192264-88-2 C₂₃H₃₀ClN₆O₈P 
• 1192264-83-7 C₂₂H₂₉ClN₇O₉P 
• 1192264-82-6 C₂₃H₃₀ClN₆O₉P 
• 1250830-04-6 (S)-2-{(4-chlorophenoxy)[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy]phosphorylamino}propionic acid isopropyl ester 
• 1273029-20-1 C₂₅H₂₉ClFN₆O₇P 
• 1613590-86-5 C₂₄H₃₀ClFN₃O₁₁P 
• 1238579-41-3 C₂₄H₃₀ClN₄O₉PS 
• 1613590-85-4 C₂₂H₂₈ClFN₃O₁₀P 

Relevant articles and documents

SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF

Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such as a Picornavirus and/or Flaviviridae infection with one or more nucleosides, nucleotides and nucleotide analogs.

SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF

Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HCV infection with one or more nucleotide analogs.

Nucleoside Aryl Phosphoramidates for the Treatment of RNA-Dependent RNA Viral Infection

The present invention provides nucleoside aryl phosphoramidates of structural formula (I) which are precursors to inhibitors of RNA-dependent RNA viral polymerase. These compounds are precursors to inhibitors of RNA-dependent RNA viral replication and are