92-72-8

Basic information

• Product Name: N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide
• Synonyms: Sanatol ITR;Solunaptol ITR;Ultrazol IX-ITR;N-(2-HYDROXYNAPHTHOYL)-2,4-DIMETHOXY-5-CHLOROANILIDE;N-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-HYDROXY-2-NAPHTHAMIDE;NAPHTHOL AS-ITR;NAPTHOL AS-ITR;5'-CHLORO-3-HYDROXY-2',4'-DIMETHOXY-2-NAPHTHANILIDE
• CAS NO: 92-72-8
• Molecular Formula: C₁₉H₁₆ClNO₄
• Molecular Weight: 357.79
• EINECS: 202-182-9
• Product Categories: Organics;pigments
• Mol File: 92-72-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 200 °C
• Boiling Point: 480.3 °C at 760 mmHg
• Flash Point: 244.3 °C
• Appearance: /
• Density: 1.371 g/cm³
• Vapor Pressure: 7.52E-10mmHg at 25°C
• Refractive Index: 1.682
• Solubility: soluble in Dimethylformamide
• PKA: 8.65±0.40(Predicted)
• CAS DataBase Reference: N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide(92-72-8)
• EPA Substance Registry System: N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide(92-72-8)

Safety Data

• Hazardous Substances Data: 92-72-8(Hazardous Substances Data)

Usage

Description

N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide is a gray or green powder with a melting point of 193-194°C. It is insoluble in water and sodium carbonate but soluble in pyridine, ethanol, and benzene, and easily soluble in acetone. In sulfuric acid, it forms a yellow liquid and displays green fluorescence, while in sodium hydroxide solution, it forms a yellow liquid. It is stable in air.

Uses

Used in Textile Industry:
N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide is used as a dyeing and printing agent for cotton fabrics, PVA, viscose, silk, and acetate fibers. It provides medium affinity and coupling ability with cotton, resulting in bright colors and good fastness.
Used in Pigment Manufacturing:
N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide is also used in the manufacture of pigment fast, contributing to the production of high-quality pigments for various applications.

Preparation

5-Chloro-2,4-dimethoxybenzenamine?and 3-Hydroxy-2-naphthoic acid condensation.

InChI:InChI=1/C19H16ClNO4/c1-24-17-10-18(25-2)15(9-14(17)20)21-19(23)13-7-11-5-3-4-6-12(11)8-16(13)22/h3-10,22H,1-2H3,(H,21,23)

Upstream product

• 97-50-7 5-chloro-2,4-dimethoxyaniline 
• 92-70-6 3-Hydroxy-2-naphthoic acid 

Downstream Products

• 61858-14-8 3-(5-chloro-2,4-dimethoxy-phenyl)-2-imino-2,3-dihydro-naphtho[2,3-e][1,3]oxazin-4-one 

Relevant articles and documents

Fluorescent substrates for potential use in enzyme-linked immunosorbent assay of membrane-bound nucleic acids

A number of phosphorylated fluorochromes were synthesized and tested for the alkaline phosphatase-linked fluorescence assay of membrane-bound nucleic acids. 3-Hydroxy-N-2′-biphenyl-2-naphthalenecarboxamide phosphate ester (HBNP) was found to be the most suitable for the assay. Nonfluorescent HBNP is hydrolyzed by phospholipase bound to the probe DNA to the highly fluorescent 3-hydroxy-N,2′-biphenyl-2-naphthalenecarboxamide (HBN). HBN is insoluble enough in aqueous medium to precipitate on the nylon membrane. Spots containing as little as 5 fg of λ DNA can be successfully detected on the membrane with HBNP.